Purpose: This study aims to generate an integrated understanding of nurses’ emotional labor by synthesizing qualitative evidence and proposing implications for practice and organizational support. Methods: A qualitative metasynthesis was conducted using a meta-ethnographic approach informed by Noblit and Hare’s interpretive synthesis method. Six qualitative studies exploring nurses’ experiences of emotional labor in South Korea were synthesized across diverse practice contexts, including inpatient wards, outpatient clinics, emergency departments, and community-based visiting nursing. Findings from each study were repeatedly read, compared, and translated into one another to identify shared meanings and higher-order interpretations, resulting in synthesized themes and an overarching line of argument. Results: Four themes were identified: First, nurses calibrated emotional expressions between standardized expectations of kindness and professional identity and routinely managed emotional displays to sustain care, education, coordination, and mediation roles. Second, emotional labor extended beyond emotion management to situational control under asymmetric power dynamics and safety threats, including verbal abuse, intimidation, sexual harassment, and context-specific risks such as solitary home visits. Third, isolation and work intensification accelerated burnout, as chronic understaffing, time pressure, ambiguous role boundaries, and insufficient managerial mediation accumulated unresolved emotional strain, contributing to withdrawal and turnover intentions. Fourth, nurses reconstructed professionalism through meaning-making and recovery resources, drawing on patient appreciation, professional pride, peer support, cognitive reappraisal, and experiential learning; however, personal coping had limited capacity to offset structural hazards. Across themes, the core experience involved enduring and regulating emotions to preserve professionalism amid unstable, conflict-prone interactions. Conclusion: Nurses’ emotional labor is a relational and structural phenomenon shaped by service norms, organizational metrics, workplace safety conditions, staffing and workload realities, and hierarchical culture. Interventions should move beyond individual-level training to multilevel strategies, including clarifying role boundaries and response standards, institutionalizing violence prevention and rapid support systems, redesigning staffing and workflow, strengthening supportive leadership and peer debriefing, and embedding accessible recovery resources within organizations.