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De novo Acute Myeloid Leukemia with JAK2 V617F: A Case Report
- 언어ENG
- URLhttps://db.koreascholar.com/Article/Detail/636
The Medical Journal of Chosun University
(조선대학교 의대논문집)
Vol. 38 No. 1 (2013.03)
pp.20-22
pp.20-22
조선대학교 의학연구원
(Institute of Medical Science, Chosun University)
초록
JAK2 V617F mutation is a common event in chronic myeloproliferative disorders. However, de novo acute myeloid leukemia with JAK2 V617F is rarely encountered. The authors report the case of a 74-year-old male with de novo acute myeloblastic leukemia without maturation (AML M1) and a JAk2 V617F heterozygotic mutation. Despite treatment with standard AML regimens, the patient died 2 months after a diagnosis of acute leukemia. This case of an AML patient with a JAK2 V617F mutation with a poor prognosis suggests that despite its rarity, a JAK2 V617F mutational study be considered for prognostic purposes in AML.
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