In this study, a medicinal herbal plant, Cinnamomum cassia, was extracted by three different methods using water, methanol, or ethanol. For anti-helicobacter activity screening, inhibitory zone tests as an in vitro assay were performed respectively with the extracting compounds. As the result of inhibitory zone test, Cinnamomum cassia extract exhibited strong anti-helicobacter activity. In addition, we performed a comparison of the antibacterial activities according to the extracting methods of Cinnamomum cassia against Helicobacter pylori. The 70% ethanol-extracted compound exhibited stronger anti-helicobacter activity than the compounds extracted with water or methanol. These results indicate that it can be used for treatment against H. pylori infection and protected against H. pylori-induced pathology using 70% ethanol-extracted Cinnamomum cassia.

• Okjin Kim(Center for Animal Resources Development, Wonkwang University, Digestive Disease Research Institute, Wonkwang University) Corresponding author
• Hyun-A Lee(Korean Medicin(KM)-Based Herbal Drug Reserch Group, Korea Institute of Oriental Medicine)
• Sunhwa Hong(Center for Animal Resources Development, Wonkwang University)
• Yung-Ho Chung(Department of Companion Animal and Animal Resources Science, Joongbu University)