The aim of study to investigate the phytochemicals and biological activities the bark of Betula schmidtii. The studies consisted of the solvent extraction, followed by the isolation of phenolic components 1~3 from ethyl acetate-soluble fraction of Betula schmidtii Bark. Their chemical structures were identified as arbutin (1), ρ-coumaric acid (2) and ferulic acid (3) using Ultraviolet-Visible (UV-Vis) Spectrophotometer, Electrospray Ionization Mass Spectrometry (ESI-MS) (negative ion mode), 1H-Nuclear Magnetic Resonance (NMR), 13C-NMR, 1H-1H Correlation Spectroscopy (COSY) and 1H-13C Hetero Nuclear Multiple Quantum Correlation (HMQC) spectral data. Compounds 1~3 shows the anti-oxidant effect with IC50 values of 29.74±1.52, 21.32±1.07 and 34.41±1.24 in 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity, respectively. Also, compounds 1~3 exhibited mushroom tyrosinase inhibitory activity with IC50 values of 31.14±1.07, 42.54±1.46 and 69.22±1.43 μM, respectively.

Abstract
서 론
재료 및 방법
    1. 실험재료 및 시약
    2. 시료 추출 및 분획
    3. 단일 화합물의 분리
    4. 기기분석
    5. 시료의 활성 측정
    6. 통계처리
결과 및 고찰
    1. 단일 화합물의 분리
    2. 화학구조 규명
    3. 화합물의 활성 측정
요약 및 결론
References

• 왕다혜(덕성여자대학교 자연과학대학 화학과) | Da-Hye Wang (Dept. of Chemistry, College of Natural Sciences, Duksung Women’s University)
• 정하숙(덕성여자대학교 자연과학대학 식품영양학과) | Ha Sook Chung (Dept. of Food and Nutrition, College of Natural Sciences, Duksung Women’s University) Corresponding author