대한구강악안면병리학회지 제46권 제5호 (p.75-82)

구강작열감증후군과 우울장애의 양방향 연관성 분석

Bidirectional Association between Burning Mouth Syndrome and Depression Disorders
키워드 :
BMS,Depression disorders,Bidirectional association,Conditional logistic regression analysis

목차

Abstract
Ⅰ. INTRODUCTION
Ⅱ. MATERIALSS AND METHODS
   1. 연구 자료
   2. 연구 대상
   3. 변수의 정의
   4. 통계 분석
Ⅲ. RESULTS
   1. BMS와 우울장애의 인구학적 특성
   2. BMS 및 우울장애와 관련된 위험 요인들
   3. BMS와 우울장애의 발생률
   4. BMS와 우울장애의 양방향 연관성
Ⅳ. DISCUSSION
Ⅴ. CONCLUSION
REFERENCES

초록

Background: The purpose of this study was to determine the bidirectional association between burning mouth syndrome (BMS) and depression disorders. Methods: A total of 854 pairs of BMS and 58 999 pairs of depression disorders matched 1:1 for age and sex were analyzed using conditional logistic regression models, which were adjusted for potential confounding factors. Results: Bidirectional analysis found that BMS was associated with depression disorders (odds ratio=4.64, P < 0.001) and depression disorders was also significantly associated with BMS (odds ratio=2.97, P < 0.001). Conclusion: These findings indicate a significant bidirectional association between BMS and depression disorders. The odds ratios suggest that BMS is a stronger predictor for incidence of depression disorders than depression disorders predicting incidence of BMS. Given this retrospective cohort design, the mechanisms underlying the association between BMS and depression disorders are not directly analyzed. Therefore, further investigation are needed to analyze the causality between BMS and depression disorders.