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        검색결과 998

        724.
        2010.06 KCI 등재 서비스 종료(열람 제한)
        ‘대흑’은 밥밑용 특성이 우수한 단경 내재해 다수성 신품종 육성을 목표로 대립 장류용 품종인 대황콩과 단경 내도복 내재해 다수성 계통인 밀양 79호를 1997년 인공교배하여 계통 육종법으로 선발한 YS1298-2B-20-5-1-1-1 계통이다. 계통명은 ‘밀양158호’이고 품종등록번호는 No. 3009이며 주요특성은 다음과 같다. 1. ‘대흑’의 신육형은 유한신육형이며 화색은 자색이고 엽형은 환형이다. 모용 및 성숙기의 협은 갈색이며 종피색과 제색은 흑
        725.
        2010.06 KCI 등재 서비스 종료(열람 제한)
        Obesity has become one of the main public health problems. Saussurea lappa (Asteraceae), syn Aucklandia lappa and Saussurea costus, is a well-known herbal medicine that has been used for treating various ailments, such as inflammatory and gastrointestinal diseases. The present study examined the anti-obesity effect of S. lappa extract (SLE) in 3T3-L1 adipocytes and high fat diet (HFD)-induced obese mouse model. SLE significantly inhibited the differentiation from preadipocytes to adipocytes of cultured 3T3-L1 in dose-dependent manner. In addition, SLE significantly decreased the body weight gain and the food efficiency ratio of mice fed HFD during 9 weeks. Further study must be performed for the pharmacological mechanism and safety of SLE as well as the identification of active compound in SLE. Our results revealed that S. lappa suppresses the adipogenesis in cultured cells and the obesity in rodent models. Therefore, S. lappa may be useful toward the development of new potent anti-obesity drugs.