The calculation of the wind field for resource assessment is done by using CFD Reynolds-Averaged Navier-Stokes simulations performed with the commercial software WindSim. A new interface has been created to use mesoscale simulation data from a meteorological model as driving data for the simulations. This method makes it necessary to take into account thermal effects on the wind field to exploit the full potential of this method. The procedure for considering thermal effects in CFD wind field simulations as well as the impact of thermal effects on the wind field simulations is presented. Simulations for non-neutral atmospheric conditions with the developed method are consistent with expected behavior and show an improvement of simulation results compared with observations.