Understanding climate change is not only complex but also extensive. Humanity has never embarked on such a huge challenge of trans-national scope: a problem that began in the past continues now and will be continuing for a long time in the future. Nepalese have also significantly felt the impact of global climate change. The scenarios of climate change indicate that the increased temperatures will cause snow-melt which will result in floods, droughts, and uneven weather patterns. The impact of such unexpected climate hazards and weather patterns have already been felt and will continue to be felt in Nepal. These climate change-induced hazards and risks particularly threaten the agriculture sector, which results in food insecurity and makes poor and vulnerable people face increasingly unanticipated impacts to their lives and wellbeing. This paper explores the climate vulnerability of the Nepalese in terms of their physical, social, economic and primarily agricultural losses due to the increasing impact of climate change. The paper argues the need for a timely adaptation of measures to maintain an environment suitable for agriculture and for the well-being of the population residing in the area.