The changes of the Fourth Industrial Revolution (Industry 4.0) are inevitable in all areas of daily life, from government to healthcare and commerce, including the educational field. Education 4.0 brings potential challenges to schools around the globe, such as digital technology, personalized data, and a connected world. Thus, this paper presents a Mexican case study about a classroom enhanced with digital technology to study the challenges that both students and teachers face to acquire and transmit the skills and competencies that Industry 4.0 requires. As a preliminary result, we found that the probability of students accepting this technology for learning is very high.