Infection is common in neutropenic patients who have hematologic malignancies. Pyomyositis forms abscesses in the skeletal muscle withStaphylococcus aureusas the most common pathogen. Patients with pyomyositis who also have hematologic malignancies are rare especially when the primary diagnosis was the malignancy. In addition, to the authors’ knowledge there are no reports of Pseudomonas species as the myositis pathogen.