Swine atrophic rhinitis is a respiratory disease that causes nasal turbinate loss and septal deformation due to Bordetella bronchiseptica and Pasteurella multocida. Turbinate loss facilitates pathogens to infect lungs, which leads to various respiratory diseases and productivity reduction. In this study, descriptive analysis was implemented for atrophic rhinitis and pneumonia. From 6 pig farms shipped to slaughterhouses in Chungbuk province, 20 heads and 20 lungs were collected by each farm from March 2020 to September 2020. Their atrophic rhinitis lesions and lung lesions were scored and blood samples were also collected to test the seroprevalence of several respiratory diseases. Pasteurella multocida from nasal swab was cultured and antibiotic resistance tests were performed. Correlation between atrophic rhinitis scores and lung lesion scores was not found. Abdominal nasal lesions were more severe than dorsal lesions. Differences in lung lesion scores were relatively small between lobes. The score of pneumonia was higher in castrated pigs than in female pigs. There was no relationship between lesion score and seroprevalence of respiratory diseases. Antibiotic resistance levels for Pasteurella multocida differed by farm, and several antibiotics were not effective. The results of this study imply that antimicrobial susceptibility tests are highly recommended before administration.

이 연구는 국립공원에 서식하고 있는 조류를 대상으로 국립공원 생물다양성을 평가할 수 있는 지수를 개발하여 생물다양성이 서식지 변화나 환경변화로 인해 영향을 받는 것을 알아보기 위한 것이다. 산림성 조류로 두견목, 딱다구리목, 수리목, 매목, 비둘기목, 쏙독새목, 올빼미목, 참새목 등에 해당하는 112종에 대하여 5인의 전문가 의견을 통해 교란 민감도 값을 산출한 후 자연성 지수 값을 산출하였다. 교란 민감도는 긴꼬리딱새와 팔색조가 높았으며 까치, 직박구리, 멧비둘기는 가장 낮게 나타났으며 각 공원에서 기록된 개체수 합과는 역상관으로 나타났다. 조류 자연성 지수는 속리산에서 78.70, 월악산 68.30, 주왕산 60.64, 월출산이 49.09로 나타났으며 특정 개체수를 지닌 종이 사라지는 시나리오별로 전체 종수와 Fisher’s alpha, Shannon-Wiener 다양도지수 (Hʹ), 자연성 지수가 차이를 나타내었다. 자연성 지수는 희귀종에게 민감한 반응을 나타내었고 개체수가 많은 종으로만 구성되는 경우에도 지역 별 차이를 나타내었다. 추후 전체 조류 종에 대한 교란 민감도 지수를 산출하여 지점별 그리고 시간에 따라 조류의 자연성 지수가 어떻게 변화하는가를 모니터링한다면 기후 변화를 포함한 다양한 환경변화로 생물다양성이 어떻게 변화하는가를 나타내는 지표로 이용될 수 있을 것으로 기대한다.

Background: Mucoepidermoid carcinoma (MEC) is the most common malignant epithelial tumor of the salivary gland in the oral cavity. In South Korea, it occurs most frequently in the palate, retromolar area, floor of the mouth, buccal mucosa, and other areas of the oral cavity. MEC is rare in children and adolescents under 20 years of age, but it is the most common malignant salivary gland tumor in this group. Reconstructive surgery is often required due to cystic lesions or resection of malignancy in the oral cavity. Buccal fat pad (BFP) is a flap that is reliable and suitable for reconstructing oral defects because it has a low complication rate and small volume change over time. Case Presentation: We report the case of a 12-year-old female patient with low-grade MEC on light soft palate with no neck metastasis. After tumor resection the palatal mucosal defect was reconstructed with a BFP flap. Conclusion: The purpose of this article is to discuss the features and treatment methods of MEC that is rarely occurring in children, and the usefulness of BFP for reconstruction. Therefore, we will make a precise diagnosis and treatment as we examine the clinical feature and review the literature.

철골보통중심가새골조의 수직불균형력에 대한 설계 요구사항이 KBC2009에서 처음으로 도입하였고, 이를 통하여 설계지진에서의 인명안전성능이라는 목표내진성능을 만족하도록 유도하고 있다. 그러나 수직 불균형력의 영향이 ASCE7-10에서 암시적으로 제시하는 최대고려지진에서의 구조물 붕괴방지성능에 미치는 영향에 대한 연구는 매우 제한적으로 이루어지고 있어 KBC2009를 따라 설계된 철골보통중심가새골조의 붕괴성능을 조사할 필요가 있다. 이를 위하여 본 논문에서는 역V형 철골보통중심가새골조의 최대고려지진에서의 붕괴양상을 조사하였다. 두 가지 지반조건과 세 가지 다른 수직불균형력 조건을 해석변수로 하여 총 6개의 5층 규모의 철골보통중심가새골조 표본건물을 설계하였다. 비선형 정적해석과 비선형 동적해석을 통하여 표본건물들의 내진성능과 붕괴양상을 조사하였다. 해석결과를 통해 수직 불균형력은 철골보통중심가새골조의 내진성능에 지대한 영향을 미쳤고, 바람직한 붕괴양상과 붕괴방지성능을 달성하기 위하여 불균형력에 대한 적절한 고려가 필요한 것으로 나타났다.

The object of this paper is to examine the noise generating mechanism at manufacturing process of metal material products. To accomplish the object; A noise generating mechanism of high noise machine, which is mounted in the small and medium size enterprise, was investigated. The measurement method of the noise for the machine by manufacturers were investigated. The noise at the 250 point of the manufacturing procrss machine in the 40 processes of the 3 factories, 3 business fields was measured. The database of the noise was built from the measurement data. The major sound sources and frequency range for the manufacturing processes of metal product machine was investigated.

The object of this paper is to evaluate a working environment noise at manufacturing process of metal material products. To accomplish the object; An employee noise exposure criteria, which is mounted in big size enterprise, was investigated. The noise at the 460 points of the manufacturing process machine in the 38 processes of the 1 factories were measured. The database of the noise was built from the measurement data. The major sound sources and frequency range for the manufacturing process of metal material product machine was investigated. In this study, we compare working environment noise criteria of korean with employee noise exposure criteria

The object of this paper is investigate noise source at metal material product manufacturing plant and create noise map for predict noise. The plant is located close to a residential area, and residents noise exposure damage expected. Through this research 68 points noise sources were measured. And according to analysis result, 30 percent of noise sources are measured above 90dB(A). Based on this measurement results were create a noise map, and comparison between the predicted noise and the background noise. The noise maps were calculated by noise prediction software using measurement data, GIS data, ESRI SHP files and actual survey data. As a analysis result, metal material products manufacturing plants are will have an effect by noise on the nearby residential area.

The present authors recently gave an analytical method for estimating three spring constants Kr, Ks, and Kt, for sidewall stiffnesses of radial tires. These represent the radial, lateral, and in-plane rotational directions respectively. The method is based on netting theory with special consideration to stiffness of the rubber matrices in the sidewall These theoretical results were verified by experiment to have sufficient accuracy. In order to confirm the availability of these spring constants, the twisting stiffness Rt of a radial tire has been analyzed in the present paper by using a spring-supported ring model. An explicit formula for Rt, expressed in terms of the three components of the spring constant, was obtained. Experiments were conducted on a 175SR14 radial tire by increasing the inflation pressure while keeping the tread circumference constant. The theoretical results agreed well with the experimental results. A related problem is also referred to; this is the forced lateral vibration with fundamental eigen-modes of the inflated sidewall-rim system when the tread is fixed. Eigen-frequencies calculated by using those spring constants coincide well with the experimental results.

The object of this paper is to examine the noise generating mechanism at manufacturing process of metal material products. To accomplish the object; A noise generating mechanism of high noise machine, which is mounted in the small and medium size enterprise, was investigated. The measurement method of the noise for the machine by manufacturers were investigated. The noise at the 250 points of the manufacturing process machine in the 40 processes of the 3 factories, 3 business fields was measured. The database of the noise was built from the measurement data. The major sound sources and frequency range for the manufacturing process of metal material product machine was investigated.

This research was planned and executed to evaluate how the composition of Yack-sun (oriental diet therapy) tea can effect the health conditions of people who are suffering from diet-related diseases such as being overweight, obese and hyperlipidemic, by taking Yack-sun tea in a form of nutritional supplement with daily meals. We produced Kangjieum with Lycense Mill., Polygonum multflorum Thunb, Cassia tora L., Crataegus pinnatifida Bge and Salvia miltiorrhiza Bge. We evaluated the effects of this tea on serum lipids, on homocysteine concentration, and on active oxygen contents, oxidative stress by clinical practices. We have determined that this tea has a significant effect on decreasing body fat content, decreasing total cholesterol, decreasing LDL-cholesterol, and decreses triglyceride and homocysteine concentrations. In addition, blood active oxygen content and oxidative stress were significantly decreased. We think that scientific and objective evaluation was performed on the components of Kangjieum prescription. We concluded that we could apply the components, not only in a form of tea, but also in other forms of various foods. The information we received from this conclusion will be basic information on how we can apply oriental medicinal resources into other food and will be a steppingstone for medicinal herbs to place a foot in the field of functional food research, which already draws sizable attention world-wide.

This research was planned and executed to evaluate how the composition of Yack-sun tea can affect the health conditions of people who are suffering from diet-related such as being overweight, are obese and have hyperlipidemia, by taking Yack-sun tea in a form of a nutritional supplement with our daily meals. We produced Kangjieum with Lycium chinense Mill., Polygonum multflorum Thunb, Cassia tora L., Crataegus pinnatifida Bge and Salvia miltiorrhiza Bge. Thus, we approach of oriental diet therapy area research of Kangjieum and analysis proximate composition, water soluble antioxidant content. The content(%, dry basis) of total carbohydrate was 60.23%, crude protein was 18.18%, crude ash was 11.36% and crude fat was 10.23% in Kangjieum. Total water soluble antioxidant content was 1.027 ㎍/㎖ of Kangjieum. We think that scientific and objective evaluation was done on the components of the Kangjieum prescription. This basic data could help guide the application of oriental medicinal resources into other foods and serve as a stepping-stone for use of Kangjieum in the burgeoning field of nutraceutical foods. Last, the scientific effects of oriental medicinal foods developed according to oriental medicinal theory. This theory is believed to be essential for government policy development concerning validation of medicinal effects and assessment, with the aim of fostering systematic development and providing guidance to food development in the interest of national health.

Agaricus blazeiMurill is an edible mushroom distributed in Brazil and presently cultivated in other areas, including Korea, Japan, and China. Its chemical components, including steroids and lectin and various polysaccharides have been widely studied. For this, we used U937/vector and U937/Bcl-2 cells, which were generated by transfection of the cDNA of the Bcl-2 gene. As compared with U937/vector, U937/Bcl-2 cells exhibited a 4-fold greater expression of Bcl-2. Treatment with 0.5 or 4 mg/ml A. blazei Murill for 24 h produced morphological features of apoptosis in U937/vector cells, respectively. This was associated with caspase-3 activation and PARP degradation. In contrast, A. blazei Murill-induced caspase-3 activation and PARP degradation and apoptosis were significantly inhibited by z-DEVD-fmk in U937 cells. Bcl-2 overexpressing cells exhibited sustained caspase-3 activation and expression levels of the Bcl-2 proteins during A. blazei Murill-induced apoptosis. In addition, these findings indicate that Bcl-2 inhibits A. blazei Murill-induced apoptosis by a mechanism that interferes with Bcl-2 degradation and activity of caspase-3 that is involved in the execution of apoptosi.

The purpose of this study is to measure the changes of regional cerebral blood flow (rCBF) and blood pressure (BP) of Cortex Acanthopanacis in rats, and to determine the effect of Cortex Acanthopanacis on phenylephrine (PE) induced contraction of isolated rat thoracic aorta. The measurement was continually monitored by laser-doppler flowmeter (Transonic Instrument, USA) and pressure transducer (Grass, USA) in anesthetized adult Sprague-Dawley rats through the data acquisition system composed of MacLab and Macintosh computer. Contractile force was measured with force displacement transducer under 1.5 g loading tension. The result of this experiment was as following; 1. Cortex Acanthopanacis did not effect the changes of rCBF and blood pressure significantly. 2. Contractions evoked by phenylephrine were decreased significantly by Cortex Acanthopanacis 3. L-NNA, ODQ, atropine and indomethacin significantly altered the relaxation of Cortex Acanthopanacis. 4. Propranolol did not change the relaxation of Cortex Acanthopanacis. These results indicate that Cortex Acanthopanacis did not change the rCBF and BP, but Cortex Acanthopanacis can relax PE induced contraction of isolated rat thoracic aorta and that this increasing contraction related to endothelium and various mechanism.

본 논문은 강섬유의 일부를 철근집합체로 대체하여 초고강도 섬유보강 철근 콘크리트 I 형보의 연성거동을 유도하는 것을 목적으 로 한다. 강섬유와 철근집합체의 조합을 가진 초고강도 콘크리트 I 형보 대한 휨거동 실험을 수행하였다. 강섬유의 혼입률은 0%, 0.7%, 1%, 1.5%, 2%이다. 철근집합체와 PS강연선 집합체가 압축구역에서 콘크리트를 구속하기 위해 사용되었다. 철근집합체와 강연선 집합체의 길이 도 실험요소 중 하나이다. 이러한 실험요소를 조합하여 9개의 초고강도 철근 콘크리트 I 형보를 제작하였다. 강섬유 뿐만 아니라 종방향의 철근 집합체도 초고강도 철근 콘크리트 I형 보의 연성거동을 유도하는데 효과를 가지고 있다. 강섬유 혼입률 0.7% 또는 1%와 철근집합체를 사용한 조합이 I형 보의 효과적인 연성 거동을 보여주고 있다. 하중과 처짐관계 및 균열양상 등이 좁은 간격을 가진 작은 직경의 종방향 철근 집합체의 유용성을 나타내고 있다.

철도차량에 의한 진동은 지반을 통해 주변 지역에 영향을 주고 피로균열등 구조적 손상을 주고 있다. 본 논문은 새롭게 개발된 탄성 스페리컬 받침을 기존 강재스페리컬 받침과의 비교를 통한 진동저감성능에 대해 평가하였다. 탄성스페리컬 받침은 반구형 곡률과 크기를 변경함으로써 현장 여건에 맞는 강성을 구현할 수 있는 장점이 있다. 탄성 스페리컬 받침은 반구형 고무 및 보강판의 적층 받침으로써 성능특성을 확인하기 위해 설계와 해석결과를 비교하고 특성시험을 실시하였다. 또한 진동저감성능 확인을 위해 열차의 실대차 축소모형 시험을실시하였다. 해석적 검증비교를 통한 특성시험에서는 설계하중 500kN 시험체의 압축 및 회전 시험결과 압축보다 회전에 의한 강성 증가가적은 것으로 확인되었다. 또한 압축 및 회전 시험 후 시험체에 외관변형 및 영구적인 손상, 찢어짐 등은 발견되지 않았다. 축소 스케일 진동측정 시험에서는 실대차 모형을 1/50축소하여 교량의 진동을 측정하였다. 그 결과 강재 스페리컬 받침에 비해 탄성 스페리컬 받침의 진동저감능력이 탁월한 것으로 판단되며, 거리별 진동감쇠 성능도 높은 것으로 확인되어 탄성스페리컬 받침의 철도교 적용 시 진동저감효과가우수할 것으로 판단된다. 향 후 실제 철도교량에서의 현장실험을 통해 성능을 검증할 계획이다.