This study evaluated the risk of single and combined exposure to microplastics in zebrafish (Danio rerio) through biomarkers, such as survival rate, excretion rate, and histological alterations of organ systems. The experimental groups were the control (Cont.), single microplastics exposure group (MPs, 1.83%/fish total weight (g)), the copper group (Cu, 21.6 μg L-1), and a group with combined exposure to MPs and copper (MPs*Cu). The experiment was conducted with individual exposure (7 days) for MP excretion rate analysis and group exposure (14 days) for biomarker analysis. The daily excretion rate of MPs tended to decrease in a time-dependent manner. The copper concentration in the body was not significantly different between single and combined copper exposure. The degeneration of mucous cells in the skin, capillary dilation of the gill lamella, increased intestinal mucous, hepatocyte hypertrophy, and the degeneration of glomeruli and renal tubules were observed in all exposure groups. These histological alterations showed the highest tendency in the MPs*Cu group. In this study, the changes in biomarkers were attributed to the single effect of copper or the combined effect of copper and MPs rather than being solely influenced by MPs.

PURPOSES : This study aimed to analyze the primary maintenance procedures and safety inspection checklist characteristics for suspension bridges. The study referred to the current suspension bridge safety management manual and conducted an on-site safety inspection. By comparing and analyzing any missing or inadequate inspection and management procedures, the study identified major inspection and management areas requiring improvement, and proposed potential solutions. METHODS : The study referred to the current suspension bridge safety management manual and conducted on-site safety inspections. By comparing and analyzing any missing or inadequate inspection and management procedures, the study identified major inspection and management areas requiring improvement, and proposed potential solutions. RESULTS : The study found that suspension bridges are currently inefficiently managed compared to other facilities subject to more rigorous maintenance and safety inspection. Therefore, maintenance and safety inspection procedures require improvement. CONCLUSIONS : For effective safety management and to reduce potential accident risk factors arising from negligent management, major improvements were suggested. Scientific maintenance and safety management could be achieved by incorporating enhancements into statutory requirements and improving management and inspection procedures. This long-term approach is likely to be more economical than the current methods, which lead to higher maintenance and repair costs and increased social costs from traffic accidents.

PURPOSES : Carbon dioxide (CO2) is a cheaper and easier to installer fire suppressant than other extinguishing gases and is easy to install, but extinguishes fires by is suffocation. As a result, suffocation accidents continue to occur in facilities equipped with CO2 fire-extinguishing facilities, Emission standards have yet to be established. This study aims to address the issue. METHODS : To effectively remove CO2 emitted from installed systems, we reviewed and analyzed previous related research and existing international standards. RESULTS : In protected areas where CO2 fire-extinguishing systems are installed, emission facilities should discharge the emitted CO2 before it enters the protected spaces. CO2 sensors can determine whether safe entry is possible or whether respirators are required. CONCLUSIONS : This study presented a specific installation method for emission facilities capable of actively discharging CO2. Applying this method is expected to contribute to improving safety in facilities equipped with CO2 fire-extinguishing facilities.

PURPOSES : This study aimed to secure the work space in alarm valve rooms to ensure stable working conditions for the engineers. METHODS : We analyzed situations where alarm valve room work spaces were inadequately secured posing a problem. Using the Ovako working posture analysis system (OWAS) method, we measured the body size of adult male technicians and their tools to analyze the actual space needed for them to maintain a healthy posture while working. On this basis, we proposed regulations governing workspace size and acceptable durations for unstable body postures. RESULTS : By measuring valve room work space and technician body size, we found that the workspace was inadequate for technicians. Applying OWAS showed that securing more space in the valve room improved the construction stability. CONCLUSIONS : Regulations on valve room size and appropriate work space for technicians will improve construction and inspection stability. This reduces the probability of poor construction and inadequate inspection, increasing the reliability of the firefighting facility system.

PURPOSES : Sprinkler facilities play a crucial role in extinguishing fires in the early stages of a building blaze. Data indicate that more than 96% of fires are suppressed by sprinklers before growing out of control. However, corrosion and pitting of the sprinkler piping can reduce system performance as facilities age. The purpose of this study is to develop an eco-friendly water-soluble corrosion inhibitor to improve the reliability and longevity of sprinkler piping. METHODS : This study compared and analyzed silicate-based sprinkler piping shrinkage agents as corrosion inhibitor against existing commercial options. Tests were conducted to evaluate reactivity with fire extinguishing water, including electrolyzed reduced water and normal water. The anticorrosive performance of the silicate-based corrosion inhibitor was evaluated under various conditions to establish suitability before potential development or commercialization. RESULTS : The new corrosion inhibitor demonstrated eco-friendly performance. In testing, none of the primary four hazardous substances that pose the most risk of harm to the human body (specifically, arsenic (As), lead (Pb), cadmium (Cd), and mercury (Hg)) were detected. The inhibitor effectively reduced corrosion of carbon steel (SPP), with weight loss rates averaging 0.12% and not exceeding 0.27%. For copper (CDA 110) weight loss rates were up to 0.03%. Testing under constant temperature and humidity conditions show that the inhibitor kept weight loss was below 0.002 g, with no significant numerical value for the weight loss rate. Overall, the results indicate the potential for an environmentally-safe corrosion inhibitor. CONCLUSIONS : The optimal silicate-based sprinkler system can provide real-time sensor information such as oxygen saturation, pH concentration, and total dissolved solids (TDS). These metrics are closely related to the aging process. By linking this system with an aging monitoring solution, maintenance costs and safety could be improved over the lifespan of the sprinkler system. The sensors and monitoring capabilities are expected to enhance maintenance efficiency and equipment reliability.

PURPOSES : This study aims to propose drone-command standard operating procedure (SOP) guidelines and Analyze their potential application to increase the use and utility of drones in urban disaster situations. Although the effectiveness and efficiency of obtaining disaster-situation information through drones have been verified by previous studies and practical experience, a survey of actual drone usability indicated a utilization rate of only approximately 4.13%. METHODS : To provide guidance for improving drone command SOPs, prior research and relevant literature were reviewed to identify commonalities between disaster-response command and control and drone use. A sample of 73 active-duty firefighters, including incident commanders (ICs) and drone pilots, were surveyed and interviewed. The data were analyzed and categorized to establish the reasons why drones are not actively used in urban disaster-response procedures. RESULTS : The primary reasons identified for not actively utilizing drones in urban disaster areas were the lack of a drone command and control system and the lack of clear criteria for when to use drones in disaster situations. In addition, many problems were found in drone-operation procedures, including emergency flight approval, securing takeoff and landing sites, and accident burden due to urban flight obstacles. To address the issues identified, standards were proposed for the type, size, and scope of urban disasters requiring drone response; for accident-prevention on basic missions and through flight safety procedures; and for installing a video transmission and reception system to easily share drone video information with ICs. CONCLUSIONS : Application of the drone-command SOP guidelines to actual urban disaster situations by disaster type will help to improve the efficiency of information acquisition and flight safety. This is expected to enable increased drone utilization. In future, extension of the research reported in this paper beyond the Seoul metropolitan area via additional follow-up studies has the potential to establish applicability of the proposed SOP guidelines to a wide variety of environments and organizational characteristics.

of hazardous risk factors, risk estimation and determination steps by reflecting the trend of overseas risk assessment. METHODS : In deriving, estimating and determining risk factors, comparing the procedures presented by the ILO with the domestic guidline to find out the differences in procedural. and, According to the domestic manual, after setting the criteria for determining a deterministic perspective, analyze the risk assessment data of a specific domestic company and three overseas risk assessment research data to analyze the differences in methodology domestic and abroad. RESULTS : Within the country, there is a possibility that a deterministic view may be applied to all stages of procedure, and certain corporate data to the risk estimation and determination stage. In the case of overseas, the trend of applying deterministic perspectives to the risk determination stage was confirmed. CONCLUSIONS : Present the need for a standard model for improving deterministic methods in the other two stages, excluding risk determination in the domestic evaluation procedure.

To develop quality-improved bakery products, the influence of the partial replacement of wheat flour by Artemisia princeps leaf powder (APP) on the quality characteristics of cookies, including antioxidant activities, was investigated. Studies were carried out to evaluate the addition of different percentages of APP on the quality characteristics of cookies prepared by incorporating APP (1-4%) into wheat flour. The incorporation of APP significantly affected the cookies’ physicochemical parameters and sensory acceptance attributes. Such incorporation at different levels significantly reduced moisture content while increasing the cookie dough’s density (p<0.05). The spread ratio, loss rate, L*, and b* values of the cookies decreased, but their hardness and a* value increased significantly with increasing levels of APP substitution (p<0.05). 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-3-ethylbenzthiazoline- 6-sulphonic acid (ABTS) radical scavenging activities were significantly increased (p<0.05) with higher APP substitution and were well-correlated. Hedonic sensory results showed that cookies fortified with 2% APP generally received satisfactory and acceptable acceptance scores. Consumers seemed to prefer the cookie texture in terms of chewiness when the samples were softer and lighter but less reddish, whereas taste acceptance may be a dominant factor in overall acceptability.

Molten Salt Reactor (MSR) is one of the 4th generation nuclear power systems which is its verified technology in physically and chemically. Among the various salts used for MSR system, the eutectic composition of NaCl-MgCl2 system maintains the liquid state at around 450°C, in the same time, it has high solubility for nuclear fuel chlorides. This characteristic has high advantage for lowering the operating temperature for the MSR, which could reduce the problem of hightemperature corrosion by salt for structural materials significantly. In particular, since MgCl2 has the similar standard reduction potential with nuclear fuel, is used as a surrogate for, many basic researches have been conducted for verifying characteristic of MgCl2. It is well-known that main short-advantage of MgCl2 is hygroscopic properties. MgCl2 changes to MgCl2-xH2O state easily by absorbing moisture in air condition. The hydrated MgCl2 is producing MgOHCl by thermally decomposing at high temperature, the formed MgOHCl corrodes structural materials, even small amount of MgOHCl gives significant damage. Therefore, the purification of MgCl2 has been required for long-term operation of MSR using MgCl2 as a base salt. In this study, the purification of eutectic composition salt for NaCl-MgCl2 has been mainly performed by considering its thermodynamic properties and electrochemical characteristic, and the experimental results have been discussed.

The presence of organic components in spent scintillation liquid should be considered during all steps of radioactive waste processing for final disposal. Scintillation liquids often referred to as cocktails are generated form radiochemical analyses of radionuclides, which mainly consists of mixtures of liquid organic materials such as toluene and xylene. Typical features of these liquid organic materials are volatility, combustibility and toxicity. These are the reason why special attention must be paid to the management of liquid organic radioactive wastes. To select an appropriate waste management strategy and to design the treatment process of spent scintillation cocktails, it is required to investigate the nature of the waste such as specific radioactivity and moisture content. The analysis results of spent scintillation liquid generated at Wolsong nuclear power plants will be discussed. An overview of the technical approaches available for the treatment of organic radioactive waste will be additionally provided.

Molten salt reactor (MSR) uses fluoride or chloride based molten salt as a coolant of the system, and fuel materials are dissolved in the molten salt, therefore it can be act as both coolant and nuclear fuel. A few issues have arisen from early-stage research and development program of MSR from Oak Ridge National Laboratory, including corrosion of structural materials and fission product management. For investigating the effect of additives on corrosion of structural materials, Mg(OH)2 and MgCl2*6H2O are added into the NaCl-MgCl2 eutectic salt. Prepared chloride salt is injected into the autoclave in the glove box, as well as corrosion coupons for candidate structural materials for molten chloride salt reactor, SS316, Alloy 600, and C-276 are also prepared. The temperature is set as 700°C. After 500 h corrosion experiment, the samples are taken out from the autoclave, and they are analyzed with scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS). SS316 samples show weight loss with all salt conditions, while Alloy 600 and C-276 show weight gain after the corrosion experiment.

먹노린재의 방제시기 설정을 위하여 서식지 내 발생 양상을 조사하였다. 전라남도를 중심으로 돌발 대량 발생 한 먹노린재의 발생 조사는 2023년도 벼의 모내기가 완료된 시점부터 전남 곡성군 석곡면과 여수시 화양면 일대 의 친환경단지에서 주 1회 실시하였으며, 벼의 수확이 완료되는 시점까지 진행될 예정이다. 금년도 발생 조사 결과는 지난 2021년도 결과와 비교하여 분석하고자 하였다. 현제까지의 결과, 여수시의 친환경단지 내 먹노린재 의 발생은 모내기가 완료된 이 후 2주 경과 시점에서 발견되었으며, 곡성군은 4주 경과 시점에서 발견되었고, 발생 최고점은 여수시의 경우 모내기 후 6주 경과 시점으로, 곡성군의 경우 5주 경과 시점으로 나타났다. 먹노린재 의 대발생이 지속되던 2021년도의 결과와 비교하였을 때, 2023년도 결과도 유사한 것으로 나타났다. 이에 따라, 먹노린재 친환경제재 살포 시기는 모내기 후 2주 경과 시점이 적절한 것으로 나타났으며, 2차 방제 시점에 대해서 는 추가 조사를 통해서 제안하고자 한다.

This study investigated ethopabate (EPB) residues in edible tissues of broiler chickens given in drinking water and established the withdrawal time (WT) of EPB in poultry tissues. Twenty-four healthy Ross broiler chickens were orally administered with EPB at the concentration of 3.8 mg/L for 14 days (EPB-1, n=24) and 15.2 mg/L for 7 days (EPB-2, n=24) through drinking water, respectively. After the drug treatment, tissue samples were collected from six broiler chickens at 0, 1, 3, and 5 days, respectively. EPB residue concentrations in poultry tissues were determined using LC-MS/MS. Correlation coefficient values ranged from 0.9980 to 0.9998, and the limits of detection and quantification (LOQ) were 0.03~0.09 and 0.1~0.3 μg/kg, respectively. Mean recoveries in muscle, liver, kidney and skin/fat tissues were 95.9~109.8, 108.7~115.3, 89.9~96.6 and 86.7~96.8%, respectively, and coefficient of variations were less than 17.11%. At the end of the drug-administration period (0 day), EPB was detected at levels under the LOQ in all tissues from both the EPB-1 and EPB-2 groups. According to the results of EPB residue in Ross broiler tissues, withdrawal periods of both EPB-1 and EPB-2 in poultry tissues were established to 0 day. In conclusion, the developed analytical method is suitable for the detection of EPB in poultry tissues, and the estimated WT of EPB in poultry tissues will contribute to ensuring the safety of Ross broiler chickens.

현재까지 전세계적으로 Periphyllus allogenes (개성진사진딧물)은 무시성충세대에 대한 형태학적 정보만이 보고되었다. 본 연구에서는 2021 년부터 2022년까지 한국 가평군, 홍천군에서 그동안 P. allogenes의 알려지지 않았던 간모, 유시성충 세대를 채집하여, 이들에 대하여 형태학적 정 보, 분포지역, 기주식물, 생태 사진을 처음으로 보고한다.

Selenium (Se) is known as an antioxidant mineral and heme iron is a major source for iron intake which can promote carcinogenesis in the body. This study was to investigate the effect of Se on heme-aggravated colon carcinogenesis in mice. Three experimental groups included control [normal diet + AOM (10 mg/kg body weight in saline)/DSS (2% in the drinking water)], [AOM/DSS + hemin (534 mg/kg body weight in CMC)], and [AOM/DSS + hemin + Se (2.82 mg/kg diet in CMC)] groups. Colonic mucosa were stained with 0.3% methylene blue and the colonic polyps, aberrant crypt (AC) and aberrant crypt foci (ACF) were counted. Lipid peroxidation in liver was evaluated by the thiobarbituric acid-reactive substances (TBARS) assay. The number of polyps in the hemin + Se group was 31.6% lower than that in the control group, and 41.4% lower than that in the hemin group. The number of AC in the hemin + Se group was 42.8% lower than that in the control group, and 49.1% lower than that in the hemin group. The number of ACF in the hemin + Se group was 49.0% lower than that in the control group, 45.7% than that in the hemin group. Hepatic TBARS level in the hemin + Se group was significantly low compared with the control group or the hemin group (p<0.05). These findings suggest that Se treatment may be protective against colon carcinogenesis promoted by a high heme-containing diet.

From 2020, Korean Animal and Plant Quarantine Agency has reset the withdrawal time (WT) for veterinary drugs typically used in livestock in preparation for the introduction of positive list system (PLS) program in 2024. This study was conducted to reset the MRL for amprolium (APL) in broiler chickens as a part of PLS program introduction. Forty-eight healthy Ross broiler chickens were orally administered with APL at the concentration of 60 mg/L (APL-1, n=24) for 14 days and 240 mg/L (APL-2, n=24) for 7 days through drinking water, respectively. After the drug treatment, tissue samples were collected from six broiler chickens at 0, 1, 3 and 5 days, respectively. Residual APL concentrations in poultry tissues were determined using LC-MS/MS. Correlation coefficient (0.99 >), the limits quantification (LOQ, 0.3~5.0 μg/kg), recoveries (81.5~112.4%), and coefficient of variations (<15.5%) were satisfied the validation criteria of Korean Ministry of Food and Drug Safety. In APL-1, APL in all tissues except for kidney was detected less than LOQ at 3 days after drug treatment. In APL-2, APL in liver and kidney was detected more than LOQ at 5 days after treatment. According to the European Medicines Agency’s guideline on determination of withdrawal periods, withdrawal periods of APL-1 and APL-2 in poultry tissues were established to 3 and 2 days, respectively. In conclusion, the developed analytical method is sensitive and reliable for detecting APL in poultry tissues. The estimated WT of APL in poultry tissues is longer than the current WT recommendation of 2 days for APL in broiler chickens.

본 연구는 신생아 검사 중 포수클로랄(chloral hydrate)을 투여 후 진행되는 신생아 진정 검사 대비 진정 대체 방식 중 하나인 피드 및 랩(feed and wrap) 방식의 유용성을 평가한 연구이다. 본 연구에선 진정으로 진행한 신생아의 두뇌 T2 축면 영상과 피드 및 랩 방식으로 진행한 같은 영상 각 30개의 운동 허상(motion artifact)과 백질과 회백질의 구분 정도를 두 명의 영상의학과 전문의가 정성적으로 평가하였고, 운동 허상을 측정하기 위해서 위상부호화(phase encoding) 방향의 배경 영역(background area)의 평균 신호 강도(mean signal intensity)를 구하여서 정량적 방식으로 평가하였다. 또한 총검사 시간을 정리한 뒤 정량적 방식으로 평가하였고 투약 기록의 여부와 간호일지를 토대로 피드 및 랩 방식의 총 39건의 검사 건수 대비 성공률을 측정하였다. 운동 허상의 정량적 평가와 영상 품질의 정성적 평가 모두에서 두 집단은 유의미한 차이가 없었으나, 검사 시간의 정량적 평가에선 p값이 0.001로 유의한 차이가 있었다. 피드 및 랩 방식의 총검사 건수 대비 성공률은 100%였다. 결론적으로 본 논문에선 피드 및 랩 방식과 진정 방식의 영상 품질이 유의한 차이가 없고 성공률이 높기에 유용하다고 판단하였으나, 검사 시간이 더 지연되는 한계가 있다는 사실을 확인하였다.