We present mm observations with the IRAM 30m radiotelescope of the HCN (J=1-0) and HCO+ (J=1-0) emission lines from Giant Moleculat Clouds (GMC) in the disk of the Andromeda Galaxy, The selected GMC targets have various morphology and environments, including locations within spiral arms or in interarm regions and with galactocentric radii ranging from 2.4 to 15.5 kpc over the disk. The radial distributions of the ratios HCN/CO and HCO+ /CO are discussed and their values are compared to other galaxies.