This study investigates the factors influencing the usage of PSAU Mobile Application by the students at Prince Sattam bin Abdulaziz University (PSAU). This study used Technology Acceptance Model (TAM) as a framework to predict the factors influencing 67 students’ usage of PSAU M-Application. The results of this study were consistent with the TAM framework in predicting the actual usage of the PSAU mobile application for academic activities. The results indicated a significantly positive association of the perceived ease-to-use with perceived usefulness, significantly positive associations of the perceived ease-to-use and the perceived usefulness with the attitude toward the usage of the PSAU’s mobile application, a significantly positive association of the perceived usefulness with the behavioral intention toward the usage of the PSAU’s mobile application, a significantly positive association of the students’ attitude toward the usage of the PSAU’s mobile application with the behavioral intention of using the application, and a significantly positive association of the behavioral intention with the actual usage of the PSAU’s mobile application. The results of this study should be useful to educational policymakers at PSAU University and elsewhere, as there is an opportunity to enhance the existing technology or adopt new technologies for academic activities.