As genotyping is becoming more of a commodity, the bottleneck in functional marker development is more and more shifted towards phenotyping. For this reason we invested in building a Crop Phenome Center at the KeyGene Wageningen facility at which we investigated various approaches for phenotype quality improvements. The KeyGene Crop Phenome Center focuses on a robust phenotyping platform in a greenhouse setup (PhenoFab) that allows for digital phenotyping as an approach to acquire more precise phenotypic data. The phenotyping is based on imaging technology and uses the potential of a track that moves all plants fully automated through the greenhouse compartment and scanning areas. The plants grow in individual containers and are photographed at pre-set points in time and from different angles. This approach was validated in various projects with diverse sets of crop plants and on both plant and root development. Data and conclusions of these experiments will be presented.