Naturally occurring left ventricular hyperplasia is a rare but lethal disease. There are very few reports of this cardiac disease in captive nonhuman primates. In a colony of Macaca mulatta (Rhesus monkey) at California National Primate Research Center, a large number of rhesus macaques were diagnosed by autopsy with naturally occurring left ventricular hypertrophy without obvious underlying diseases over a 22-year period. The confirmatory diagnosis of ventricular hypertrophy was based on findings of notable left ventricular concentric hypertrophy with reduced left ventricular lumen, which is very similar to human ventricular hypertrophy cases. This report discusses an 11-year-old Macaca fascicularis monkey (Cynomolgus monkey, crab-eating macaque), weighing 2.95 kg, that was presented for enrollment in a pharmacokinetic (PK) study. During the PK experiment, the monkey died following a sudden decrease in percutaneous oxygen saturation and heart rate. Gross and histological examinations of the heart were performed. On gross pathology, the left ventricular wall was thickened, and the chamber lumen was reduced. In histopathological examination using hematoxylin- eosin and Masson-trichrome stains, fibrosis and myocyte disarray were not observed, but an increased cell density, compared to the normal heart, was confirmed. The autopsy results confirmed left ventricular hyperplasia as the major cause of death.

Since the directly bonded interface between TiAl alloy and SCM440 includes lots of cracks and generated intermetallic compounds(IMCs) such as TiC, FeTi, and Fe2Ti, the interfacial strength can be significantly reduced. Therefore, in this study, Cu is selected as an insert metal to improve the lower tensile strength of the joint between TiAl alloy and SCM440 during friction welding. As a result, newly formed IMCs, such as Cu2TiAl, CuTiAl, and TiCu2, are found at the interface between TiAl alloy and Cu layer and the thickness of IMCs layers is found to vary with friction time. In addition, to determine the relationship between the thickness of the IMCs and the strength of the welded interfaces, a tensile test was performed using sub-size specimens obtained from the center to the peripheral region of the friction-welded interface. The results are discussed in terms of changes in the IMCs and the underlying deformation mechanism. Finally, it is found that the friction welding process needs to be idealized because IMCs generated between TiAl alloy and Cu act to not only increase the bonding strength but also form an easy path of fracture propagation.

본 연구는 우리나라 전국 무역항 중 입항 선박이 많은 주요 4개 항만을 선정하여 10일간의 AIS 실측 자료를 분석하였다. 실측 조사로 산출한 주요항만의 피크시간 혼잡도는 시간당 평균혼잡도 보다 약 3.8~5.7배 높게 나타났다. 이는 기존의 Port-MIS 통계자료로 울산항 본항의 해상교통혼잡도를 평가한 선행연구 사례에서 피크시간 혼잡도가 시간당 평균혼잡도 보다 약 1.7배 높은 것과는 많은 차이가 있어 현 항로의 교통특성을 왜곡하는 문제를 확인할 수 있다. 따라서 해상교통혼잡도를 평가할 때에는 Port-MIS 통계자료보다 실측조사를 기반으로 해상교통혼잡도를 산출하는 것이 타당하다고 본다.

본 연구에서는 비국지 탄성이론과 미분변환법을 이용하여 탄성매질속 다중 크랙을 가진 비균질 나노빔의 지배방정식을 유도하고, 유도된 지배방정식과 경계조건에 미분변환법을 적용하여 나노빔의 축방향의 진동해석을 하며, 나노빔의 첫단과 끝단의 경계조건이 각각 고정 단(Clamped end)과 자유단(Free end)의 경우에 대하여 수치해석을 수행하였다. 수치해석 결과를 기존 연구결과와 비교하여 타당성을 입증한 후, 비국지 작은 척도효과 (Nonlocal small scale effect), 탄성매질의 강성, 크랙의 위치, 크랙의 강성 그리고 비국지 탄성이론의 나노빔에 대한 진동해석 결과를 고찰하였다.