This research examines how the consumer responds to corporate advertising by a global BtoB advertiser. Based on the theory of consumer knowledge, corporate reputation, Attitude toward the Ad (Aad), and global consumer culture, this study assumes a positive relationship between Aad and corporate reputation, and in turn, word-of-mouth intentions. In addition to causal relationships, the moderating effects of level of knowledge were tested. The results showed positive causal relationships among consumer knowledge, brand attitude, and word-of-mouth communication. However, the moderating effects of level of knowledge were not fully supported. The implications and limitations of these results are discussed.