Simulated waste-derived synthesis gas has been tested for hydrogen production through water gas shift (WGS) reaction in the temperature range of 240oC ~ 400oC over supported Pt catalysts prepared by an incipient wetness impregnation method. MG30, MgO, ZrO2, Al2O3 and CeO2 were employed as supports for WGS reaction in this study. 1 wt.% Pt/ CeO2 catalyst exhibited the highest CO conversion as well as 100% CO2 selectivity. This is due to easier reducibility of Pt/CeO2 and high oxygen mobility and oxygen storage capacitiy of CeO2. Pt/CeO2 catalyst can be a promising catalyst for WGS reaction from waste-derived synthesis gas.