As technologies have been more quickly developed in this 4th Industry Revolution era, their application to defense industry has been also growing. With these much advanced technologies, we attempt to use Manned-Unmanned Teaming systems in various military operations. In this study, we consider the Location-Routing Problem for reconnaissance surveillance missions of the maritime manned-unmanned surface vehicles. As a solution technique, the two-phase method is presented. In the first location phase, the p-median problem is solved to determine which nodes are used as the seeds for the manned vehicles using Lagrangian relaxation with the subgradient method. In the second routing phase, using the results obtained from the location phase, the Vehicle Routing Problems are solved to determine the search routes of the unmanned vehicles by applying the Location Based Heuristic. For three network data sets, computational experiments are conducted to show the performance of the proposed two-phase method.