The objective of this study is to assess the impact of spray drying conditions on medium-chain triglyceride (MCT) loading, solubility, and release of an MCT-loaded solid self-emulsifying system in a water-insoluble oily substance. MCT-loaded solid self-emulsifying systems are prepared by spray drying with SDS and calcium silicate. The effects of inlet temperature (60, 80, or 100oC) and feed solution composition (0, 10, 50, 90, or 100% ethanol) on physicochemical properties of MCT-loaded solid self-emulsifying systems are studied. The inlet temperature significantly affects the water solubility of MCT. Moreover, the feed solution composition significantly affects water solubility, release rate, and MCT loading. The MCT-loaded solid self-emulsifying system obtained at 60oC using 90% ethanol feed solution shows the best physicochemical properties among the synthesized products and exhibits better water solubility (4.43 ± 0.44 vs. 0 μg/mL) and release (94.4 ± 1.6 vs. 32.8 ± 7.4%, 60 min) than a commercial product. Furthermore, the MCT-loaded solid self-emulsifying system shows an excellent emulsion droplet size (approximately 230 nm).
This study was conducted to evaluate the biofiltration treatment characteristic for benzene vapor gas. Compost and calcium silicate porous material were used as biofilter fillers. Gas velocity and empty bed retention time were 15 m/hr and 4 min, respectively. Benzene gas removal efficiency of P-Bio (calcium silicate porous material with inoculation) was the highest and maintained in over 98%. After shock input of benzene gas, the removal efficiency of P-Bio biofilter was recovered within 2 days, while 5 days were taken in CP-Bio (compost + calcium silicate porous material mixture with inoculation) and CP (compost + calcium silicate porous material mixture without inoculation) biofilters. The removal efficiency of P-Bio biofilter was near 100% in the loading rate of 〈85g/m3(filling material)/hr, It was shown that the maximum elimination capacities of P-Bio, CP-Bio, and CP biofilters were 95, 69, and 66 g/m3(filling material)/hr, respectively. Microbial number of P-Bio, which the number was the lowest at start-up, was 3 orders increased on operational day 48. CO2 was generated greatly in order of P-Bio, CP-Bio, and CP biofilters.