The safety of the future mankind becomes a world issue due to the climate change driven by global warming. It is inevitable to observe everywhere in daily life the impact of climate change. The level of emergency differs between long-term, mid-term, and short-term, which depends on situation. The impact of climate change in daily life is fairly diverse, and therefore multiple research units of different backgrounds often work together on the measuring and forecasting of the impacts. This paper aims to study the potentially useful methods to analyze and forecast the impact on the changes in transport activities of Canadian Inuit. This is part of the research on the climate change’s impact on the Northern Sea Route area. Either natural or man-made change of external environment forces human to adjust their daily life in order to maintain their utility level of life. Individual or individuals’ group react to the external impact, the way of which differ from others. This fact calls a simulation research on the whole set of input-intermediate process-output. Agents representing individuals or certain subpopulation are given a set of rules to react to stimulus and interact with other agents behave in the realm of simulation. This paper provides methodological discussions on how analyzing and forecasting future change in transport activities in response to climate change. The discussion goes around activity-based approaches that are recently popular in urban planning and transportation planning among available simulation approaches. This paper then discusses the implication and future research agenda.