In the FMAS system the effect of iron on alumina solubility in orthopyroxene has been determined by experiments with crystalline starting mixtures of garnet and orthopyroxene of known initial compositions at 20 kb, 975˚C and 25 kb, 1,200˚C. These data have been modeled to develop a thermodynamic method for the calculation of Al2O3 in orthopyroxene as a function of P, T and composition. The direct application of the alumina solubility data in the MAS system to natural assemblages could lead to significant overestimation of pressure, probably by about 5kb for the relatively common garnet-lherzolites with abot 25 mol per cent Ca + Fe2+ in garnet and about 1 wt. per cent Al2O3 in orthopyroxene since the effect of Fe is similar to that of Ca and Cr3+in reducing the alumina solubility in orthopyroxene in equilibrum with garnet relative to that in the MAS system.