Acinetobacter baumannii is one of the most problematic causative agents of nosocomial infections, especially in the immune compromised or patients in intensive care units. In recent years, as multiple antibiotic resistant A. baumannii has increasingly emerged, it has become difficult to treat infections effectively. The authors report a case of extreme drug resistant A. baumannii bacteremia caused by catheter-related infection, as confirmed by blood and catheter tip culture, in a 63-year-old man. The patient responded well to 24 days of doripenem and colistin treatment.