Recently, the air pollution have bad effects on the indoor environment. Many buildings around the world use natural ventilation. to remove the air pallutant. But, nowadays, ventilation requirements can be demanding, as modern systems require greatly improved reliability and control. The fan and the duct are used to remove air mechanically from the space. Until now, apartment houses have been relying on the duct supply system ventilation rather than other system ventilations. Therefore, the establishment of a prediction method based on optimal ventilation energy consumption using duct supply system and ductless is the ultimate goal of this study. As a result, this study found that the characteristics of duct and ductless supply system ventilation are dependent to each exhaust system. Consequently, the local supply indices of the duct supply system is definitely superior about 24.6% ~ 26.4 % than those of ductless supply system. However, the duct supply system has greater pressure drop in ventilation area than ductless, and duct system needs a lot of ventilation energy. In this study, The ductless supply system has advantage over the duct system about 14.8 % as duct exhaust system and 20.0% as ductless exhaust system in terms of modified local supply indices.