A two-hour fire-resistance PC hollow slab for residential use was developed to secure structural and fire-resistance performance and to be applied to the general building and apartment housing markets. Compared to the existing hollow slab, in order to secure the same or better structural performance and economic feasibility by reducing the quantity, it was attempted to secure the fire resistance performance by reducing the concrete filling rate in the cross section and adjusting the thickness of the upper and lower flanges by optimizing the hollow shape in the cross section of the slab. For structural performance evaluation, experiments were performed on PC hollow slabs by varying the member thickness and the presence or absence of overlaid concrete, and all of the experimental results showed that the design strength was sufficiently exhibited and that stability during construction was possible. The developed synthetic PC hollow slab has secured fire resistance and residential performance so that it can be applied to all buildings, and it is intended to be immediately applied to the field.