The concept of RIS(Regional Innovation System) has widely been used in discourse and policy issues in Korea. But most studies of RIS concern on BT or IT industries combining with diverse regional agencies in urban areas. Some other studies were concentrated on general ideas or concept of the RIS. The purposes of this study are (1) to suggest a analytical method to select specialized industry in local autonomy, (2) to analyze the relationship between specialized industry and gross sales of agricultural products and stock farm products, (3) to analyze the relationship between gross sales of agricultural products and stock farm products and GRDP, and (4) to construct a model of RIS that fits particularly for rural areas. This study particularly accentuates that a specialized industry is more meaningful when it can raise GRDP, which eventually can give positive effect of RIS on regions.