Nowaday many researches has proved that glutaradehyde(GA) is more excell ent medicament in vital p띠 potomy practice than formocresol (FC) . But a number of dental practitioner prefer to use formocresol in vital pulpotomy procedure todays And thus author reeva luate proper ties of gluteraldehyde and formocresol through implantation into epidermis and trypsin digestion after f ixation at 2% buffered glutar aldehyde and Burkley's formocresol solution.. And then prepared t issues were s tained by H&E a nd Masson-TI’ ichome method. GA showed definite fixative zone and γery low diffusi ble property in epi dermis and pulp t issue as glutaraldehyde and formocresol were compared. GA r epresented exceedingly lower antigenici ty than FC GA fixation exhibited more resistibility to trypsin digestion than FC. As considering these results‘ it concluded that GA would be extremely supe ri 이 . medicament to formocresol in vital pulpotomy proce