The paternal sex ratio (PSR) chromosome is considered as an extremely selfish genetic element. It has only been found in the two hymenopteran insects- Nasonia and Trichogramma- with haplodiploid sex determination. When an egg is fertilized by sperm bearing PSR, the paternal genome is destroyed by PSR soon after fertilization resulting in haploid restoration and the egg develops into a male with only the maternal genome and PSR itself. Recently PSR is paid much attention, since it may be used for controlling haplodiploid pests. PSR can be successfully transferred from its natural host, T. kaykai to the novel host, T. deion. In the two hosts another sex ratio distorter, Wolbachia, is found. Wolbachia is a cytoplasmically inherited bacterium that induces parthenogenesis in this genus resulting in female offspring production without fertilization. The transmission efficiency of PSR in T. deion is lower than that in T. kaykai and is negatively influenced by the Wolbachia infection. The results show that 1) there is a negative host genetic background effect on the transmission of PSR in the novel host, 2) the transmission efficiency becomes even lower, when PSR males are infected with Wolbachia. The results imply that complex interactions among the bacterium, PSR and the species specific genetic background.