Purpose - The development of Anhui high-tech industry is the key to transforming the mode of economic development and optimizing the industrial structure. Research design, data, and methodology - The data of paper that is the data of Anhui province and the six provinces of central China from 2010 to 2015, which analyzed the present situation of High-tech industry in Anhui Province by means of data comparison and literature analysis, and then explored several possible modes of undertaking. Results - With the analysis of the current situation of the development of high-tech industry in Anhui Province, several possible modes for undertaking the transfer of high-tech industries in Anhui Province were explored: The mode of undertaking of Leading Enterprises + Industrial park, the mode of undertaking of differentiated development + Regional comprehensive exploitation and the mode of undertaking "Dynamic industrial Chain" + industrial cluster. Conclusions - Based on the perspective of industrial upgrading, this paper analyzes the shortcomings of Anhui Province in the traditional mode of undertaking industrial transfer and expounds the inherent requirements of innovation industry undertaking. Finally, on the basis of the above analysis, the author explored three possible modes of acceptance.