The aim of this study was to investigate radiographic features of osteosclerosis on digital panoramic radiographs. Osteoscleosis was diagnosed with its radiographic features of amorphous non- expansible radiopacity with unknown etiology. In diagosing osteosclerosis, differential diagnosis is needed from periapical cemental dysplasia, osteoma, benign cementoblastoma, and anatomic structures. Fifty-eight osteosclerosis on digital panoramic radiopgraphs from 46 patients with osteoscleosis were selected for this study. All of the osteosclerosis were found in the mandible. Among them, 53(91.4%) occurred on the posterior region. The mean diameter was 9.1㎜. The internal structure was radiopaque in 39(67.2%) and mixed radiolucent and radiopaque in 19(35.3%). There was no specific effect on the surrounding structures. In 16(27.6%), partial or complete radiolucent margin was noted which might be digital image artifact by enhancement.