In Korea, nuclear regulation is supervised by the Nuclear Safety and Security Commission (NSSC). The area that required expertise in regulatory activities has been entrusted to the Korea Institute of Nuclear Safety (KINS) and the Korea Institute of Nuclear Nonproliferation and Control (KINAC) affiliated to the NSSC. Such nuclear regulatory activities should be implemented fairly and objectively because they directly affect nuclear operators and the entire nuclear industry. In addition, as the recent policy trend has flowed in the direction of improving the business efficiency and quality of public institutions, a study was intended to improve the overall regulatory quality of the institution. First, a case study was performed on the quality management system of domestic and foreign related organizations, including the Department of Energy (DOE) and the Nuclear Regulatory Commission (NRC) in the US. Through study and analysis of the system, it was attempted to derive institutional quality requirements for KINAC and to establish a plan to use the requirements as major items of Internal Quality Control (IQC) system. By analyzing the quality management systems of research institutes such as Brookhaven National Laboratory (BNL) and Electronics and Telecommunications Research Institute (ETRI) as well as regulatory authority, the characteristics of KINAC that conduct R&D necessary for regulation were reflected. Based on this study, the quality management system leading to IQC-EQA (External Quality Assurance) -TQM (Total Quality Management) will be established continuously to improve the business quality of regulatory authority.