A novel vibration control method for vibration reduction of a spacial structure subjected to earthquake excitation was proposed in this study. Generally, spatial structures have various vibration modes involving high-order modes and their natural frequencies are closely spaced. Therefore, in order to control these modes, a spatially distributed MTMDs (Multiple TMDs) method is proposed previously. MR (Magnetorheological) damper were used to enhance the control performance of the MTMDs. Accordingly, MSTMDs (Multiple Smart TMDs) were proposed in this study. An arch structure was used as an example structure because it has primary characteristics of spatial structures and it is a comparatively simple structure. MSTMDs were applied to the example arch structure and the seismic control performance were evaluated based on the numerical simulation. Fuzzy logic control algorithm (FLC) was used to generate command voltages sent for MSTMSs and the FLC was optimized by genetic algorithm. Based on the analytical results, it has been shown that the MSTMDs effectively decreased the dynamic responses of the arch structure subjected to earthquake loads.