Background: Recent cases of spinal cord infarction combined with cerebral infarction have demonstrated improved walking ability through pharmacological treatment and rehabilitation. However, studies on the efficacy of multidisciplinary approaches remain limited. Objectives: This study aimed to investigate rehabilitation strategies and establish a foundation for clinical practice, focusing on physical and occupational therapy for patients with spinal cord and cerebral infarctions. Design: A case study. Methods: A 70-year-old woman with combined spinal cord and cerebral infarction underwent 20 weeks of rehabilitation. Functional outcomes were assessed using Grip Strength, Manual Muscle Test (MMT), Trunk Impairment Scale (TIS), Manual Function Test (MFT), Berg Balance Scale (BBS), 10-Meter Walking Test (10MWT), and Korean Modified Barthel Index (K-MBI). Results: Over 20 weeks, Grip Strength improved to 6 kg (left) and 13 kg (right), MMT increased from 97 to 103 points, and TIS improved from 2 to 10 points. MFT scores increased to 18 (left) and 25 (right). BBS improved from 1 to 23 points, and the 10MWT time decreased to 19.84 seconds. K-MBI scores rose from 12 to 39 points. Conclusion: A multidisciplinary approach, including robotic therapy, significantly improved functional recovery, facilitating reintegration into daily life.