The occupational injury and illness(OII) was influenced by the various factors. This study was planned to investigate the pathway of the activities of OSHM on the rate of OII via worker's participation. The survey on the trend of the activities of OSHM was used. The sample size of manufacturing industry was 3,000 enterprises and that of construction was 1,000 enterprises. The survey was done by interview method with structure questionnaire. Questions about the activities of OHSM were integrated into one category using factor analysis. The enterprises with OII has more activities of OSHM than that without OII. Among enterprises with OII, the level of the activities of OSHM was positively correlated with the rate of OII. The activities of OSHM has influenced on the rate of OII directly and indirectly via worker's participation and the activities of prevention of accident. Worker's participation also has the direct effect and indirect effect on the rate of OII. Worker's participation in construction sector has more effect on OII than that in manufacturing sector.