This paper aims to develop a conceptual framework for evaluating the impact of motivational factors on the work results of lecturers at Vietnam National University, Hanoi (VNU), one of two leading multidisciplinary and multi-sectoral national universities in Vietnam. This study has considered wages and other benefits (WB), training and development (TD), working environment (WE) and working motivation (WM) as motivational factors, and proposed a structural model of the impact of motivational factors on the work results of lecturers at VNU. The empirical analysis used data from the survey data of 321 university lecturers. Comprehensive, valid, and reliable tools (SPSS 26 and SmartPLS 3.0 software) are used to evaluate rigorous statistical tests including convergence validity, discriminatory validity, reliability, and average variance extracted to analyze and verify the gathered data, and the hypotheses developed. The result of path analysis shows that four motivational factors constitute a structured system with different degrees of influence on the work results of lecturers. There is also a positive relationship between the motivational factors and the work results of lecturers. As a result, it can be concluded that all hypotheses developed are supported. Several recommendations are further suggested to improve the performance of lecturers at VNU.