As a method of seismic-design for pile-supported wharves, equivalent static analysis, response spectrum analysis, and time history analysis method are applied. Among them, the response spectrum analysis is widely used to obtain the maximum response of a structure. Because the ground is not modeled in the response spectrum analysis of pile-supported wharves, the amplified input ground acceleration should be calculated by ground classification or seismic response analysis. However, it is difficult to calculate the input ground acceleration through ground classification because the pile-supported wharf is build on inclined ground, the methods to calculate the input ground acceleration proposed in the standards are different. Therefore, in this study, the dynamic centrifuge model tests and the response spectrum analysis were carried out to calculate the appropriate input ground acceleration. The pile moment in response spectrum analysis and the dynamic centrifuge model tests were compared. As a result of comparison, it was shown that the response spectrum analysis results using the amplified acceleration in the ground surface were appropriate.