From the short-period variability survey (SPVS), we obtained time-series BV CCD images in the region of an open cluster M50 (NGC 2323) for 10 nights from 2008 February 9 to 27. The observation was performed using a small refracting telescope ( ϕ=155mm, f=1050mm) in Bohyunsan Optical Astronomy Observatory (BOAO). M50 is included in the observing field of ASAS (The All Sky Automated Survey). In the region of M50, we found 8 new variable stars including two δ Scuti stars with short-periods and very small amplitudes. There are known nine variable stars by the catalogues of ASAS and GCVS in the region. We confirmed the variability of the known variable stars for six and non-variability for three.