The IMO has established a regulation for the ECDIS installation on ships based on the IHO S-57 standards. The ECDIS supports sailors in achieving a safe voyage by using ENCs and monitoring the information of their ship. However, the S-57 standards were developed as edition 3.1 and prohibited revision for more than 20 years. So, the IHO developed a new standard as S-100 into the hydrography and maritime field instead of updating the S-57 to edition 4.0. In this study, the new S-100 ECDIS was developed and verified with ENCs and the digital maritime safety information by using a ship steering simulator and by conducting an on-board sea-trial test. It evaluated the impact on ship operations if the next-generation navigation support system is introduced. Based on this research, the S-100 ECDIS will generate improvements such as safe voyages by providing various of real-time safety information and up-to-date data to ship and sailors.