Glycosyl acrylate and methacrylate were synthesized by lipase-catalyzed esterification of vinyl acrylate and vinyl methacrylate with β-methyl glucoside in t-butanol as a reaction medium. At the optimum conditions of initial concentration of 150g/l β-methyl glucoside, molar ratio of 1 : 3, 5%(w/v) lipase(Novozym 435) and 50℃, we attained up to 100% conversion for enzymatic glycosylation of vinyl acrylate and vinyl methacrylate by supersaturated solvent process. The polymerizable glycosyl acrylates and methacrylate are expected to have biomedical application as hydrophilic monomers and hydration modifiers to be used for biocdmpatible hydrogel.