Thick-walled pressure vessel has been autofrettaged in order to improve the fatigue life of the pressure vessel. The compressive tangential residual stress near the bore of the pressure vessel due the autofrettage process is benefical to the fatigue crack initiation and propagation of the pressure vessel. However, a reverse yielding due to the Bauschinger effect during the unloading process in autofrettage causes the reduction of the compressive residual stress near the bore. In order to evaluate the fatigue crack propagation life of the autofrettaged thick-walled pressure vessel, the Bauschinger effects were considered. Stress intensity factors of the crack at the inside surface of the pressure vessel due to operating pressure loading of 707 MPa and autofrettage loading with different levels of overstrain were calculated by using finite element methods, and used for evaluating fatigue crack propagation lives. Fatigue lives of the pressure vessel with the Bauschinger effects resulted in 45% to 67% reductions in fatigue life compared to those of the pressure vessel with ideal residual stress distributions depending on the autofrettage level.