This study aims to compare the effects of different types of test-items using the same text and test-takers' text familiarity on the scores of English reading comprehension. A total of 312 third-grade Korean high school students took three different English tests, adapting types of test-items from the Korean College Scholastic Ability Test (CSAT). Each test included items using the same texts, presented in exam preparation books published by EBS in Korea, but different question types. To estimate levels of their topic familiarity, two surveys were carried out. Repeated measures ANOVAs reveal that there were significant differences in scores among the items using the same text with different types of test-items. However, there was no statistically significant effect of topic familiarity. The results indicate a greater effect of different types of test-items than topic familiarity on the scores of a reading comprehension test using the same text. Based on the findings, it is suggested that English teachers in Korea need to manage their reading classes by using various types of questions in order to develop students' reading ability and to prepare their students for the CSAT.