Reverberation mapping (RM) is an ecient method to investigate the physical sizes of the broad line region (BLR) and dusty torus in an active galactic nucleus (AGN). The Spectro-Photometer for the History of the Universe, Epoch of Reionization and Ices Explorer (SPHEREx) mission will provide multi-epoch spectroscopic data at optical and near-infrared wavelengths. These data can be used for RM experiments with bright AGNs. We present results of a feasibility test using SPHEREx data in the SPHEREx deep regions for torus RM measurements. We investigate the physical properties of bright AGNs in the SPHEREx deep eld. Based on this information, we compute the eciency of detecting torus time lags in simulated light curves. We demonstrate that, in combination with complementary optical data with a depth of  20 mag in B􀀀band, lags of  750 days for tori can be measured for more than  200 bright AGNs. If high signal-to-noise ratio photometric data with a depth of  21{22 mag are available, RM measurements are possible for up to  900 objects. When complemented by well-designed early optical observations, SPHEREx can provide a unique dataset for studies of the physical properties of dusty tori in bright AGNs.

This study was undertaken to evaluate the toxic effect of cadmium sulfate (Cds) on planarians (Dugesia japonica), and the suitability of planarians as an alternative animal model for toxicity studies. Planarians were exposed to varying concentrations of experimental solutions containing 0.1–25 mg/L Cds, and incubated for 1, 3, and 5 hrs. Motility, seizure-like behaviors (c-like, head-bop, snake-like, and screw-like) and regeneration ability of the amputated fragment were subsequently evaluated. Results showed decreased motility with increasing concentrations of Cds (p<0.05), with the lowest motility being observed at the highest concentration of 25 mg/L Cds. Results also indicate that seizure-like behavior patterns were significantly affected by increments in the Cds concentrations, especially the c-like and head-bop behaviors were notably increased. Compared to the control, the regeneration ability of the planarians was decreased in the experimental solutions containing Cds. Planarians exposed to Cds showed either delayed eye formation or no eye regeneration during incubation. Moreover, increased concentrations of Cds resulted in failure to regenerate and death of the planarians. In conclusion, this study confirm that the heavy metal Cds exerts a toxic effect on planarians. Furthermore, the performances of the planarians in the experimental period exhibit their suitability as an alternative animal model for toxicity studies.

Background/Aim: Endoscopic retrograde cholangiopancreatography (ERCP) training requires varying degrees of staff assistance regarding operation of the fluoroscopy machine via a foot pedal. Efficiency is important to acquire during this training due to radiation risks. In this study, we evaluate the effect of controlling endoscopy and fluoroscopy unit on duct cannulation rates (CRs) and total fluoroscopy time (FT) for fellows in training. Methods: 204 patients undergoing ERCP were randomized to one of two groups: 1) “Endoscopist Driven” group in which the endoscopist controlled the foot pedal for fluoroscopy, and 2) “Assistant Driven” group in which attending or fellow controlled the foot pedal while the other team member controlled the endoscope. Various measures including selective duct CR and total FT were recorded. Results: There was no significant difference in mean procedure duration between the two groups (32 minutes vs. 33 minutes, p=0.70). There was also no statistically significant difference in CR (83.7% vs. 77.4%, p=0.25) or FT (3.27 minutes vs. 3.54 minutes, p=0.48). Conclusions: ERCP is a technically challenging procedure which requires extensive supervision. This study demonstrates that CR and FT are not affected by who controls the fluoroscopy.

We report the discovery of a giant exoplanet in the microlensing event OGLE-2017-BLG-1049, with a planet―host star mass ratio of q = 9.53 ± 0.39 × 10-3 and a caustic crossing feature in Korea Microlensing Telescope Network (KMTNet) observations. The caustic crossing feature yields an angular Einstein radius of θE = 0.52 ± 0.11 mas. However, the microlens parallax is not measured because the time scale of the event, tE ≃ 29 days, is too short. Thus, we perform a Bayesian analysis to estimate physical quantities of the lens system. We find that the lens system has a star with mass Mh = 0.55+0.36 -0.29 M⊙ hosting a giant planet with Mp = 5.53+3.62 -2.87 MJup, at a distance of DL = 5.67+1.11 -1.52 kpc. The projected star{planet separation is aㅗ = 3.92+1.10 -1.32 au. This means that the planet is located beyond the snow line of the host. The relative lens{source proper motion is μrel ~ 7 mas yr-1, thus the lens and source will be separated from each other within 10 years. After this, it will be possible to measure the flux of the host star with 30 meter class telescopes and to determine its mass.

We investigate the plausibility of mass return, from stellar mass loss processes within the central ~100 pc region of the Milky Way (the inner nuclear bulge), as a mass supply mechanism for the Circumnuclear Disk (CND). Gas in the Galactic disk migrates inward to the Galactic centre due to the asymmetric potential caused by the Galactic bar. The inward migration of gas stops and accumulates to form the central molecular zone (CMZ), at 100{200 pc from the Galactic center. It is commonly assumed that stars have formed in the CMZ throughout the lifetime of the Galaxy and have diffused inward to form a 'r-2 stellar cusp' within the inner nuclear bulge. We propose that the stars migrating inward from the CMZ supply gas to the inner nuclear bulge via stellar mass loss, resulting in the formation of a gas disk along the Galactic plane and subsequent inward migration down to the central 10 pc region (CND). We simulate the evolution of a gas distribution that initially follows the stellar distribution of the aforementioned stellar cusp, and illustrate the potential gas supply toward the CND.

Cyanobacteria (blue green algae) blooms formed in natural water resources due to the environmental pollution produce toxic compounds as secondary metabolites, causing health hazards to both humans and other living beings. Microcystin is a well-known toxin produced by cynobacteria. The present study was undertaken to evaluate varying concentrations and exposure times of two different forms of microcystin, viz., -LR (MCLR) and -LA (MCLA), on the motility and seizure-like behavior of planarian (Dugesia japonica). Compared to control, reduced motility was observed in both the MCLR or MCLA treated groups, but did not differ significantly with increasing concentrations of microcystin. However, the number of seizure-like behaviors were increased dose-dependently in planarian exposed to MLCR or MCLA. Exposure time to microcystine also affected the motility and seizure-like behaviors of planarians; 24 hrs incubation with MCLR, and 48 and 96 hrs exposure to MCLA, showed significantly (p<0.05) lower motility, as compared to the control. Assessing regeneration of the planarians revealed the simultaneous completion of eye formation at day 9 in planarians incubated in the absence or presence of MCLR or MCLA, thereby indicating that exposure to microcystin has no effect on the process. In conclusion, we determined that exposure to microcystins resulted in decrease in the number of motility, and induced abnormal behavior pattern in planarians. Further studies are required to identify the toxicity of microcystin that affects aquatic ecosystems.

The luxury market has become a prevalent global economic sector which is estimated to reach $442 billion by 2025 (Arienti, Levato, Kamel, & Montgolfier, 2018). Sales revenue in the luxury market has grown not only in the US and EU, but also in emerging economies with rapid economic expansion, such as China and India (Shukla, 2010; Tynan, McKechnie, & Chhuon, 2010). Young consumers (i.e., millennials and Gen Z) comprise the fastest growing group of purchasers of luxury goods (D’Arpizio, Levato, Prete, Del Fabbro, & de Montgolfier, 2019). Subsequently, marketers are interested in factors that affect young consumers’ decision-making process in luxury fashion goods consumption. It is a challenge for marketers to appeal to young consumers because abrand or brand name is less important to them than it has been for older generations (Forte, 2019). Country-of-origin (CoO) is relatively important for luxury purchase compared to non-luxury purchase (Godey et al., 2012). In the context of luxury brand consumption, research suggests that attitude functions (social-adjustive, value-expressive, hedonic, and utilitarian) also have an impact on luxury purchase intentions (Schade, Hegner, Horstmann, & Brinkmann, 2016). This study thus investigates significant factors influencing luxury brand purchase among young consumers. Specifically, we draw from “Functional Theories of Attitudes” (Grewal, Mehta, & Kardes, 2004) as a framework to investigate the effects of CoO on consumers’ attitude functions and luxury brand purchase intentions.

빠른 기술변화와 복잡한 국제정세적 현실 속에서 성공하는 기업의 비결은 무엇일까? 또한 역동적인 경영환경 속에서 새로운 글로벌 리더기업으로 성장한 기업의 경쟁력은 무엇일까? 본 연구는 후 발기업이 기존의 best practice돌파하여 새로운 글로벌 혁신기업으로 성장하기 위해 필요한 전략 적 관점을 다룬다. 기존 문헌연구를 토대로 연구한 결과 빠르게 추격하는 후발주자가 새로운 글로벌 혁신기업으로 탈바꿈하기 위해서는 세 가지 조건이 필요하다. 즉, 진정한 글로벌 리더로 기업이 부상하기 위해선 1) 기업자원 내 시너지의 수준, 2) 혁신의 수준, 그리고 3) 글로벌 플랫폼 조정능력의 수준이 높아야 한다. 본 연구는 글로벌 기업의 사례분석을 통해 스마트폰 산업의 글로벌 기업들의 성장방향을 비교하여 위 세 가지 수준의 정도에 따른 경쟁우위와 리더십의 수준을 시사한다. 선두기업으로서 애플의 역량은 자원의 시너지 및 혁신이지만 글로벌 플랫폼의 영향력은 상대적으로 높지 않다. 삼성은 새로운 리더가 될 잠재성이 가장 높은 기업으로 자원의 시너지와 글로벌 플랫폼이 강한 동시에 혁신의 정도 또한 꾸준히 강화되고 있다. LG와 화웨이는 여전히 추격기업에 속해있지만 화웨이는 세 가지 역량을 빠르게 향상시키며 빠른 추격자로 성장하고 있다. 궁극적으로 본 연구는 후발주자에서 선두주자로, 혹은 일류에서 일등기업으로 성장하려는 기업이 취할 수 있는 전략적 방향으로 기업의 내부역량간 시너지, 산업의 혁신주도, 그리고 타기업 및 연관산업과의 글로벌 네트워크 역량의 중요성을 수립한다.