Purpose : The prescriptions of Dongyisoosebowon (東醫壽世保元) are so different to those of existing Korean medicine(韓醫學). Because Lee Jema (李濟馬, 1837-1900, the author of Dongyisoosebowon) has classified herbal medicines(本草) by the four Sasang constitutions(四象體質). But he has not explained his method in detail. Therefore we make a plan to analyze the herbal medicine of the Dongyisoosebowon prescription by Sung․M i․Guikyung(性․味․歸經), the essential elements of the herbal medicines, to get a idea how Lee Jema has classified the herbal medicines by four Sasang constitutions. Methods : The herbal medicines are chosen from Dongmuyugo(東武遺藁) and Dongyisoosebowon. And they are rearranged by Sung․Mi․Guikyung from Shinnongbonchokyung(神農本草經), Tangaekboncho(湯液本草) Dongyibogam(東醫寶鑑) and Imsangbonchohak(臨床本草學, Clinical Herbology). Result : The herbal medicines classified by Lee Jema have a characteristic trend by their Sung․Mi․Guikyung. In the herbal medicines of Soumin (少陰人), 81.8% of them is characterised in Warm and hot medicine (溫熱藥材) and 68.2% has its action to Bi(脾). In those of Soyangin, 75% of them is characterised in Cool and cold medicine (寒凉藥材) and 60% to Sin(腎), 25.7% to Bangkwnag(膀胱). In those of Taeumin, 63% of them is characterised in Warm and hot medicine, 47.8% in Cool and cold medicine. In all of their classifications, the result of Yakmi(藥味, taste of herbal medicine) analysis is not characteristic. Conclusion : The herbal medicines classified by Lee Jema have a characteristic trend by their Sung․Guikyung.

1. Background and Purpose For many years, Sibimikwanjungtang, Yangkyeoksanhwatang and Hyeongbangsabaeksan have been used as a therapeutic agent in constitutional disease. The effects of three prescriptions on the vascular system is not well-known. The purpose of this study is to determine the effects of these prescriptions on blood pressure(BP) and regional cerebral blood flow(rCBF). 2. Methods I injected a vein of rat with extracts of Sibimikwanjungtang, Yangkyeoksanhwatang and Hyeongbangsabaeksan with five kinds of dose and measured BP and rCBF. 3. Results After injected Sibimikwanjungtang, BP was not changed but rCBF was increased in a dose-dependent manner. After injected Yangkyeoksanhwatang, BP was elevated and rCBF was increased in a dose-dependent manner. After injected Hyeongbangsabaeksan, BP was not changed but rCBF was increased in a dose-dependent manner.