To identify possible associations with concentrations of ambient air pollutants and daily mortality in Busan, this study assessed the effects of air pollution for the time period 1999-2000. Poisson regression analysis by Generalized Additive Model were conducted considering trend, season, meteorology, and day-of-the-week as confounders in a nonparametric approach. Busan had a 10% increase in mortality in persons aged 65 and older(95% CI : 1.01-1.10) in association with IQR in NO2(lagged 2 days). An increase of NO2(lagged 2days) was associated with a 4% increase in respiratory mortality(CI : 1.02-1.11) and CO(lagged 1 day) showed a 3% increase(CI : 1.00-1.07).