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        검색결과 57

        21.
        2018.08 KCI 등재 SCOPUS 구독 인증기관 무료, 개인회원 유료
        This research is conducted to create a functional hydrogel ophthalmic lens containing nanoparticles. Carbon nanoparticles and PEGMEMA are used as additives for the basic combination of HEMA, MA, and MMA, and the materials are copolymerized with EGDMA as the cross-linking agent and AIBN as the thermal initiator. The hydrogel lens is produced using a cast-mold method, and the materials are thermally polymerized at 100 oC for an hour. The polymerized lens sample is hydrated in a 0.9% saline solution for 24 hours before the optical and physical characteristics of the lens are measured. The refractive index, water content, contact angle, light transmittance, and tensile strength are measured to evaluate the physical and optical characteristics of the hydrogel lens. The refractive index, water content, contact angle, UV-B light transmittance, UVA light transmittance, visible light transmittance, tensile strength and breaking strength of the hydrogel lens polymer are 1.4019~1.4281, 43.05~51.18 %, 31.95~68.61o, 21.69~58.11 %, 35.59~84.26 %, 45.85~88.06 %, 0.1075~0.1649 kgf and 0.1520~0.2250 kgf, respectively. The results demonstrate an increase in refractive index, tensile strength and breaking strength and a decrease in contact angle and light transmittance. Furthermore, the visible light transmissibility is significantly increased at PEG 10 %. It is clear that this material can be used for high-performance ophthalmic lenses with wettability, ultraviolet ray blocking effect, and tensile strength.
        4,000원
        22.
        2017.11 구독 인증기관·개인회원 무료
        Purpose: This research was conducted to produce the functional hydrogel ophthalmic lens containing nanoparticles. Methods: Carbon nanoparticles and PEGMEMA were used as additives for the basic combination containing HEMA, MA, and MMA, and the material was copolymerized with EGDMA as the cross-linking agent and AIBN as the initiator. The hydrogel lens was produced by a cast-mold method, and the materials were thermally polymerized at 100° C for an hour. The polymerized lens sample was hydrated in a 0.9% saline for 24 hours before the optical and physical characteristics of the lens were measured. Results: The refractive index, water content, contact angle, light transmittance, and tensile strength were measured to evaluate the physical and optical characteristics of the hydrogel lens. The results showed that the refractive index, water content, contact angle, UV-B light transmittance, UV-A light transmittance, visible light transmittance and tensile strength of the hydrogel lens polymer was 1.4019~1.4281, 43.05~51.18%, 31.95~68.61°, 21.69~58.11%, 35.59~84.26%, 45.85~88.06% and 0.0657~0.1649kgf, respectively. It showed an increase of refractive index and tensile strength while decreased in contact angle and light transmittance. Conclusions: This material can be used for ophthalmic lenses with high performance of wettability, ultraviolet ray blocking effect, and tensile strength. Furthermore, the visible light transmissibility was significantly increased at PEG 10%.
        25.
        2015.12 KCI 등재 구독 인증기관 무료, 개인회원 유료
        목 적: 친수성 콘택트렌즈의 굴절력 측정 방식 중 하나인 Wet Cell 측정법에 대한 정확도를 확인하기 위 해 망원경식 렌즈미터를 사용하여 콘택트렌즈의 정점굴절력을 측정하였다. 방 법: Wet Cell 측정용 홀더는 현재 임상에서 주로 사용하고 있는 Poster Soft Contact Lens Wet Cell 제품을 사용하였으며, 국내 제조업체의 렌즈를 함수율은 38%, 45%, 58%로 구면굴절력은 -3.00D, -7.00D, -10.00D로 분류하여 각각 실험하였다. 결 과: 망원경식 렌즈미터를 사용하여 Wet Cell 방식으로 콘택트렌즈의 정점굴절력을 측정한 결과, -3.00D의 콘택트렌즈는 함수율 38%일 경우 -3.41D로 45%일 경우 –3.41D로 그리고 함수율 58%일 경우 -2.63D로 각각 측정되었다. -7.00D의 콘택트렌즈는 함수율 38%일 경우 –7.87D로 45%일 경우 –7.20D로 그리고 58%일 경우 -5.19D로 각각 측정되었다. 또한 -10.00D의 콘택트렌즈는 함수율 38%일 경우 –10.17D 로 45%일 경우 -10.60D로 58%일 경우 -7.33D로 각각 측정되었다. 결 론: 실험 결과, 함수율이 높을수록 Wet Cell 방식에 의한 측정값은 콘택트렌즈에 표기된 굴절력에 비 해 낮게 측정되는 경향을 나타내었다. 디옵터가 높아질수록 측정 정확도 역시 신뢰도가 낮은 것으로 나타났 다. Wet Cell 방식을 사용하여 망원경식 렌즈미터로 측정 시 함수율과 디옵터별로 정확도의 차이가 발생됨 을 알 수 있었다.
        4,000원
        26.
        2015.10 구독 인증기관·개인회원 무료
        Purpose : Ophthalmic soft contact lens using functional silicone monomer were manufactured and the physical properties of copolymerized materials were analyzed. Methods : The materials for ophthalmic hydrogel contact lenses were polymerized by adding 1,3-bis(TDS) and acrylated poly-(dimethyl siloxane) to DMA, HEMA and cross-linking agent(EGDMA) which are commonly used in ophthalmic hydrogel contact lenses. The hydrogel ophthalmic lens was manufactured by cast mould method. The manufactured ophthalmic hydrogel contact lenses were stored in a 0.9% NaCl normal saline for 24 hrs. And also, for the utility of functional silicone monomer as a high gas permeability and visible light transmittance material for ophthalmologic devices, the oxygen permeability, spectral transmittance and water contact were measured. Results : The value of oxygen permeability ranges from 16.83 to 36.59 x    ×     sec ×  ×   . The results showed that the average value of water content decreased as the ratio of additive increased. The visible light tansmittance of copolymerized ophthalmic soft contact lenses, was in the range 89~ 92%. Conclusions : The material containing acrylate poly-(dimethyl siloxane) and methacrylate siloxane is expected to be used usefully as a material for high oxygen permeability hydrogel contact lens.
        27.
        2015.10 구독 인증기관·개인회원 무료
        Purpose: The optical and physical characteristics of hydrogel soft contact lens polymerized with various hydroxy substituted acrylate material were evaluated. Methods: This study used HEMA(2-hydroxyethyl methacrylate), HEA(2-hydroxyethyl acrylate), HPMA(hydroxypropyl methacrylate) with the cross-linker EGDMA(ethylene glycol dimethacrylate) and the initiator AIBN(azobisisobutyronitrile) for copolymerization. The polymerization of the contact lens material was conducted through thermal polymerization in 100℃ for about 1 hours. Results: The polymer by using thermal polymerization process for hydrogel lens was produced and the physical properties showed that the water content of the sample containing HEMA, HEA and HPMA was in the average of 37.06%, 82.12% and 21.57%, respectively. And also, refractive index of the sample containing HEMA, HEA and HPMA was in the average of 1.4330, 1.3540 and 1.4649, respectively. In case of the optical properties of the sample, the result showed that the near-UV transmittance was 82.67%, 80.32% and 79.83%, and the visible transmittance was 89.72%, 88.24% and 86.89%, respectively. Conclusions: Consequently, polymerization of the hydroxy substituted acrylate material was more shorten the molecular length, increased water content and decreased the refractive index of the soft contact lens.
        28.
        2015.05 구독 인증기관·개인회원 무료
        Purpose : UV-block effect of soft contact lens polymerized and with 2,4-dihydroxybenzophenone in the basic hydrogel contact lens material was evaluated. and also the influence of sterilization condition on change of optical properties was analyzed. Methods: 2,4-dihydroxybenzophenone as additive with 2-hydroxyethyl methacrylate and the initiator AIBN were used for thermal copolymerization. The mixture was heated at 100 ℃ for 50 mins to produce the hydrogel contact lens. and they are heated at 115 ℃ for 3 hour for sterilization. Results: The optical properties of produced contact lens including 2,4-dihydroxybenzophenone showed that the UV-A transmittance was 28~36% and the UV-B transmittance was 10~18%. and Also, in case of sterilization situation, the results showed that the UV-A transmittance was 5~17% and the UV-B transmittance was 4~16%, respectively. Conclusions: After sterilization of produced contact lens, UV-block effect of soft contact lens including benzophenone group was increased.
        29.
        2015.05 구독 인증기관·개인회원 무료
        Purpose : Recently, the eye disease associated with ultraviolet radiation were reported. In this study, the UV-block hydrophilic soft contact lens using 2-ethylhexyl trans-4-methoxy-cinnamate were manufactured and the optical properties of copolymerized materials were measured. Methods: The basic hydrophilic soft contact lens material with addition of Dhb(2,4-dihydroxy benzophenone) 0.5% ~ 1.0%, Thb(2,4,4-trihydroxy benzophenone) 0.5% ~ 1.0% and Hmb(2-hydroxy-4-methoxy benzophenone) 0.5% ~ 1.0% respectively were polymerized and the hydrophilic soft contact lens were manufactured by cast mould method. The lenses were stored in a 0.9% NaCl normal saline for analysis. Results: In the measurement of DHB samples, the optical transmittance showed the UV-B transmittance of 2.1 ~ 4.3%, UV-A transmittance of 19.0 ~ 27.2% and visible transmittance 88.8 ~ 90.1%. And also, in the case of THB samples, the optical transmittance of UV-B, UV-A and visible transmittance was 2.0 ~ 2.4%, 13.6 ~ 18.8% and 89.5 ~ 90.9%, respectively. Also, in the case of HMB samples, the optical transmittance of UV-B, UV-A and visible transmittance was 4.0 ~ 12.3%, 22.5~37.2% and 87.9 ~ 89.2%, respectively. Conclusions: Based on the results of this study, 2-ethylhexyl trans-4-methoxy-cinnamate with benzophenone materials were suitable for use as a material to UV-block hydrophilic lens.
        30.
        2015.03 KCI 등재 구독 인증기관 무료, 개인회원 유료
        목 적: 본 연구는 hydroxybenzophenone계 물질을 첨가제로 소량의 비율로 사용하여 소프트 콘택트렌 즈 제조 후 광학성 및 물리적 특성을 분석하여 콘택트렌즈 재료로서 활용도를 알아보았다. 방 법: 소프트콘택트렌즈의 주재료인 HEMA와 개시제인 AIBN을 기본조합으로 하고 2-hydroxybenzophenone, 2,4-dihydroxybenzophenone 그리고 2,4,4-trihydroxybenzophenone을 첨가제로 사용하여 각각 공중합하였다. 결 과: 2-Hydroxybenzophenone을 첨가한 콘택트렌즈의 경우 UV-A 86.8~72.2%, UV-B 84.2~70.4%로 소량의 자외선 차단 효과를 나타내었다. 또한 2,4-dihydroxybenzophenone 경우 UV-A 76.2~16.8%, UV-B 66.8~2.0%로 2,4,4,-trihydroxybenzophenone의 경우 UV-A 61.8~11.6% UV-B 50.8~1.4%로 두 물질 모두 자외선 차단 효과가 다소 있는 것으로 나타났다. 결 론: 본 실험 결과로 볼 때 소량 첨가하였을 때 2,4-dihydroxybenzophenone 및 2,4,4,- trihydroxybenzophenone의 경우 자외선 차단 기능을 가진 콘택트렌즈로 다양하게 사용될 것으로 판단된 다.
        4,300원
        31.
        2014.09 KCI 등재 구독 인증기관 무료, 개인회원 유료
        목 적: 본 연구는 안경렌즈 굴절력 측정을 위해 사용되는 렌즈미터에 대해 기존 4점 방식 자동렌즈미터 와 Shack–Hartmann 방식의 렌즈미터를 사용하여 구면 안경렌즈의 굴절력을 각각 측정하고 정확도를 분석 하였다. 방 법: 실험에 사용한 안경렌즈는 임상에서 주로 많이 사용되고 있는 국내 제조업체의 렌즈를 사용하였 으며, 제조사별로 A, B, C사의 안경렌즈를 구면굴절력에 따라 -5.00D, -10.00D, -15.00D로 분류하여 각 각 실험하였다. 결 과: 4점 방식 자동렌즈미터를 사용하여 구면렌즈의 굴절력을 측정한 결과 -5.00D는 A사 -4.89D, B 사 -4.92D, C사 -4.97D로 측정되었으며, -10.00D는 A사 -9.94D, B사 -9.94D, C사 -9.93D, -15.00D는 A사 -14.96D, B사 -14.90D, C사 -14.92D로 각각 측정되었다. Shack–Hartmann 방식 자동렌즈미터를 이 용하여 같은 종류의 구면렌즈의 굴절력을 측정한 결과 -5.00D는 A사 -5.00D, B사 -5.01D, C사 -5.02D로 측정되었으며, -10.00D는 A사 -10.00D, B사 -10.01D, C사 -10.00D, -15.00D는 A사 -15.09D, B사 -15.01D, C사 -15.08D로 각각 측정되었다. 결 론: 안경렌즈 굴절력 측정에 있어 구면렌즈의 경우 Shack–Hartmann 방식의 자동렌즈미터가 4점 방 식 렌즈미터보다 더 정확한 측정값을 나타내었다.
        4,000원
        32.
        2014.06 KCI 등재 구독 인증기관 무료, 개인회원 유료
        목 적: 본 연구는 습윤성 물질을 포함한 기본적인 하이드로젤 콘택트렌즈 재료에 silicon 2,3-naphthalocyanine bis(trihexylsilyloxide)(SiNc)를 첨가하여 친수성 콘택트렌즈의 물리적 및 광학 특성을 측정하였다. 또한 제조된 고분자의 자외선 투과율과 접촉각을 측정하여 SiNc의 안의료용 렌즈 소재로의 활용도, 특히 습윤성을 향상시키는 안의료용 고분자로서의 활용도에 대해 알아보았다. 방 법: 친수성 하이드로젤 렌즈 제조를 위해 2-hydroxyethyl methacrylate (HEMA), N-vinyl-2-pyrrolidone (NVP), methylmethacrylate (MMA), 교차결합제인 ethylene glycol dimethacrylate (EGDMA) 그리고 개시제인 azobisisobutyronitrile (AIBN)을 사용하여 공중합 하였다. 또한, SiNc는 첨가제로 사용되었다. 중합 후 제조된 콘택트렌즈 재료의 함수율, 굴절률, 접촉각 및 분광투과율 등의 물리적 특성을 측정하였다. 결 과: 생성된 하이드로젤 렌즈 고분자의 물리적 특성을 측정한 결과, 함수율 38.12 ~ 37.98%, 굴절률 1.434 ~ 1.435, 접촉각 34.33 ~ 62.91°그리고 분광투과율의 경우 34.6 ~ 91.0%의 범위로 나타났다. 또한 SiNc를 첨가한 조합에서 자외선 투과율이 크게 감소하였으며, 습윤성은 증가하였다. 결 론: 습윤성 물질 및 SiNc를 첨가하여 제조된 안의료용 고분자 재료는 자외선 차단 및 습윤성이 우수한 하이드로젤 콘택트렌즈를 제조하기 위한 재료로 유용하게 사용될 것으로 기대된다.
        4,000원
        33.
        2014.05 구독 인증기관·개인회원 무료
        Purpose: The test is designed to investigate the differences in measurement method between conventional four point method and Hartman Shack principle applied method in digital lensmeters. Methods: The lenses tested are from the most frequently used manufacturers’ ones in Korea. The lenses are from 3 different brands with spherical power of -5.00D, -10.00D, and -15.00D. Cylinder lenses are sourced with same criteria with cylinder power of C-0.50D, C-1.25D and C-2.00D. Before making the measurement, all the sample were stored in standard saline solution for at least 30 min and maintained at standard temperature. Results: The Hartman-Shack method employed digital lensmeter showed a better accuracy performance in spherical lens value measurement, meanwhile the four points method based lensmeter showed a better performance in cylinder value. For the spherical cylinder combined value lenses, the Hartman-Shack method employed lensmeter performed better than four point method based lensmeter. Conclusions: As per the minus diopter spherical cylinder lenses, the Hartman Shack lensmeter showed better accuracy in spherical values and four point method based lensmeter showed better reading for cylinder values.
        34.
        2014.05 구독 인증기관·개인회원 무료
        Purpose: Various studies have been conducted on macromolecular materials that not only have basic characteristics but also UV-blocking capabilities. Here we report tinted hydrogel contact lens containing titanium silicon oxide nanoparticles. This study also showed the physical and optical effects of 4-iodoaniline on contact lenses, which affect UV transmissibility. Methods: Titanium silicon oxide nanoparticles were used as additives. HEMA, MA, MMA, 4-iodoaniline and a cross-linker EGDMA were copolymerized in the presence of AIBN as an initiator. The physical properties such as water content, refractive index, contact angle, spectral transmittance of produced contact lenses were measured. Results: Measurement of the physical characteristics of the copolymerized material showed the water content of 38.68~35.01%, refractive index of 1.4350~1.4418, contact angel of 34.15~57.25° and spectral transmittance of 1.0~84.8%. Also, the transmittance for UV light was reduced significantly in combinations containing titanium silicon oxide nanoparticles. Conclusions: Tinted hydrogel contact lens material containing titanium silicon oxide nanoparticles is expected to be able to be used usefully as a material for UV-block hydrogel contact lens.
        35.
        2014.05 구독 인증기관·개인회원 무료
        Purpose: This study evaluated the physical and optical characteristics of hydrophilic contact lens polymerized with addition of 1-vinylimidazole in the basic hydrogel contact lens material, and in particular, the utility of 1-vinylimidazole as a contact lens material for ophthalmologic devices was investigated. Methods: This study used 1-vinylimidazole with the cross-linker EGDMA (ethylene glycol dimethacrylate), HEMA (2-hydroxyethyl methacrylate) and the initiator AIBN (azobisisobutyronitrile) for copolymerization. The polymerization of the contact lens material was conducted through thermal polymerization in 100°C for about 40 mins. To produce the high functional contact lenses, a cast mould method was used. Results: The physical properties of the hydrogel ophthalmic material were investigated by measuring the average value of refractive index, water content and optical transmittance. The refractive index of 1.4330~1.4408, water content of 36.10~38.59%, UV-A transmittance of 90.0~72.2% and UV-B transmittance of 88.6%~64.2% and visible ray transmittance of 89.2~91.8% were obtained. The transmittance for visible light was over 89% in all combinations with 1-vinylimidazole and the transmittance for UV reduced up to a certain level in certain combinations with 1-vinylimidazole. Conclusions: Based on the results of this study, the produced copolymer can be estimated to be suitable for use as ophthalmic lens material for UV- blocking effects.
        36.
        2014.05 구독 인증기관·개인회원 무료
        Purpose: The physical and optical characteristics for copolymers produced by adding 3-Iodoaniline and 3-chloroaniline to the various monomers commonly used for ophthalmic contact lenses were investigated. Methods: The basic hydrogel ophthalmic lens material with addition of 3-Iodoaniline and 3-chloroaniline respectively were polymerized by heating at 80℃ for 20 mins, and then 110 ℃ for 40 mins. To produce contact lenses, a cast mould method was used. The produced contact lenses samples underwent the pre-process by being hydrated in 0.9% NaCl saline for 24 hours. Afterward, their physical and optical properties were measured. Results: The results showed that the average value of refractive index increased and the water content decreased as the ratio of additive increased. The measurement of the optical transmittance of the copolymerized polymer with addition 3-Iodoaniline showed that the transmittance for visible ray, UV-B and UV A is 89.4~90.8%, 2.0~15.2% and 40.6~67.8%, respectively. Also, for samples with addition 3-Iodoaniline, the transmittance for visible ray, UV-B and UV-A was in the range of 89.8~90.6%, 5.0~22.2% and 57.6~73.8% respectively. Conclusions: It is expected that the results would contribute to a wider application of contact lenses containing aniline group which are to be used as ultraviolet ray blocking contact lenses.
        37.
        2014.05 구독 인증기관·개인회원 무료
        Purpose: In this study, the copolymers produced by adding the 2-hydroxypyridine and 4-hydroxypyridine were compared with the previous hydrogel contact lens materials. The utility of hydroxypyridine as a possible UV-blocking and high wettablility material for contact lenses was investigated. Methods: This study used 2-hydroxypyridine and 4-hydroxypyridine as additions with the cross-linker, EGDMA (ethylene glycol dimethacrylate), HEMA (2-hydroxyethyl methacrylate), AA (Acylic acid), MMA (methyl methacrylate) and the initiator AIBN (azobisisobutyronitrile) for thermal copolymerization. The mixture was heated at 115 ℃ for 50 mins to produce the hydrogel contact lens. Results: The polymer by using thermal polymerization process for hydrogel contact lens was produced and the physical properties which showed that the contact angle of sample containing 2-hydroxypyridine and 4-hyroxypyridine was in the range of 59.77~69.18° and 55.47~66.31°, respectively. The wettability of sample increased as the ratio of 4-hyroxypyridine increased. Also in case of 2-hydroxypyridine, the measurements showed that visible light 89.0~91.0%, UV-B 8.0~22.0%, UV-A 68.0~74.0% and in case of 4-hydroxypyridine, the results showed that visible light 88.0~91.0%, UV-B 79.0~81.0%, UV-A 84.0~86.0% respectively. Conclusions: The produced copolymer is suitable for hydrogel contact lenses with UV-blocking effect and high wettability.
        38.
        2014.03 KCI 등재 구독 인증기관 무료, 개인회원 유료
        목적: 본 연구는 2-fluoro-4-pyridinecarboxylic acid 및 6-fluoropyridine-3-carboxylic acid를 사용하여 친수성 하이드로젤 콘택트렌즈 재질을 중합하고 제조된 친수성 콘택트렌즈의 물리적, 광학적 특성을 분석하여 이들 물질들의 콘택트렌즈 재료로서의 활용도를 알아보았다. 방법: 본 연구는 카르복시산 및 불소로 치환한 피리딘을 2가지 이상 첨가제로 사용하여 친수성 콘택트렌즈의 기본적인 재질인 HEMA(2-hydroxyethyl methacrylate), AA(acrylic acid), MMA(methylme-thacrylate), 개시제인 AIBN(azobisisobutyronitrile), 그리고 교차결합제인 EGDMA(ethylene glycol dimethacrylate)를 사용하여 공중합하였다. 결과: 생성된 고분자의 물리적 특성을 측정한 결과, 굴절률 1.4348-1.4300, 함수율 33.69~35.84%, 가시광선 투과율 89.6~90.8%, 인장강도 0.2292-0.3344kgf 그리고 접촉각의 경우 76.05°~50.95°의 분포를 나타내었다. 또한 황색포도상구균에 대한 항균실험 결과 2-fluoro-4-pyridinecarboxylic acid 및 6- fluoropyridine-3-carboxylic acid를 5% 첨가했을 때 항균효과가 다소 있는 것으로 나타났다. 결 론: 본 실험 결과, 2-fluoro-4-pyridinecarboxylic acid 및 6-fluoropyridine-3-carboxylic acid를 첨가하여 제조된 친수성 콘택트렌즈는 기본적인 콘택트렌즈 물성을 만족하였으며 우수한 습윤성과 항균성 및 자외선 차단 콘택트렌즈로 활용될 수 있을 것으로 판단된다.
        4,000원
        39.
        2013.12 KCI 등재 구독 인증기관 무료, 개인회원 유료
        목적: 본 연구는 콘택트렌즈 재료로 널리 사용되는 2-hydroxyethyl methacrylate, N-vinyl-2-pyrrolidone, methyl methacrylate, ethylene glycol dimethacrylate에 titanium isopropoxide와 tungsten(VI) oxide 나노입자를 첨가하여 안의료용 렌즈 재료를 중합하였다. 방법: 안의료용 콘택트렌즈의 첨가제로 Tungsten (VI) oxide 나노입자 사용의 활용도를 조사하기 위해 tungsten(VI) oxide 나노입자를 포함한 하이드로젤 콘택트렌즈 재료의 광학적, 물리적 특성 변화를 측정하였다. 결과: 생성된 고분자에 대한 자외선 영역의 투과율은 매우 낮게 측정되어 자외선 차단 능력이 있는 것으로 나타났다. 또한 tungsten(VI) oxide 나노입자의 첨가는 함수율의 큰 변화를 나타내지 않았으나 일정비율을 첨가한 조합에서는 소량의 함수율 변화가 나타났다. 함수율의 큰 변화가 없음에도 불구하고 산소침투율의 측정 값은 tungsten(VI) oxide 나노입자의 첨가 비율이 증가할수록 계속적으로 감소하는 경향이 나타 났다. 결론: 이상의 결과를 통해 titanium isopropoxide 및 tungsten(VI) oxide 나노입자는 하이드로젤 콘택트렌즈의 기본적인 물성을 만족시키면서 기능성 콘택트렌즈 재료로 유용하게 활용될 수 있을 것으로 판단된다.
        4,300원
        40.
        2013.12 KCI 등재 구독 인증기관 무료, 개인회원 유료
        목적: 본 연구는 trimethylsilyl methacrylate와 titanium silicon oxide 나노입자를 사용하여 친수성 하이드로젤 콘택트렌즈 재질을 중합하고 제조된 친수성 콘택트렌즈의 물리적, 광학적 특성을 분석하여 이들 물질들의 콘택트렌즈 재료로서의 활용도를 알아보았다. 방법: 고분자의 중합은 2-hydroxyethyl methacrylate, methyl methacrylate 및 n-vinyl pyrrolidone과 가교제인 ethylene glycol dimethacrylate를 기본 조합으로 하였으며, 개시제로는 AIBN을 사용하였다. 제조된 렌즈의 물성 변화를 알아보기 위해 trimethylsilyl methacrylate와 titanium silicon oxide를 첨가하여 중합하고 함수율, 굴절률, 산소투과도, 분광투과율을 측정하였다. 결과: 제조된 친수성 콘택트렌즈는 하이드로젤 콘택트렌즈의 기본물성을 만족하였으며, 첨가제인 trimethylsilyl methacrylate의 양이 증가함에 따라 산소투과도는 증가하는 것으로 나타났다. 또한 titanium silicon oxide 나노입자의 첨가는 친수성 렌즈 소재의 기본적인 물성을 변화시키지 않으면서 자외선을 차단하는 것으로 나타났다. 결론: 본 연구를 통해 trimethylsilyl methacrylate와 titanium silicon oxide는 콘택트렌즈의 기본적인 물성을 만족시키면서 고산소투과성 및 자외선 차단 콘택트렌즈 재료로 다양하게 활용될 수 있을 것으로 판단된다.
        4,000원
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