The current study investigates how retailers deal with sustainability issues in different market fields with a specific focus on fashion industry. This work examines the last ten years of the scientific literature on sustainable retailing (SR), through a systematic literature review. 215 papers selected from the EBSCO database are analyzed, in order to develop an overview on the state of the art of research on SR. A comprehensive framework for a holistic definition of SR and for retailers’ practices related to sustainability is outlined. Future research directions on SR are provided.