본 연구는 4DCT를 이용하여 종양의 움직임을 분석하였다. ITV 여유에 따른 TC, II, CI를 이용하여 적절 한 균일 IM을 확인하였다. 또한 각각의 경우에서 DVH와 NTCP를 비교하였다. 균일 IM 적용 시 종양에 대한 선량 분석 결과 TC, CI, II를 모두 만족하는 최적의 치료계획은 20% 위상에서 2 mm, 40%는 3 mm로 평가되었다. 이를 PTV20, PTV40의 정상조직에 조사되는 선량과 비교하였다. 20% 방사선 조사 영역에서 폐에 대한 V5, V10, V20은 1.49, 1.26, 0.65% 증가하였고 40%는 1.9, 2.41, 1.23% 증가하였다. NTCP 역시 20%와 4 0% 각각 0.57, 0.029% 선량 증가가 있었지만 PTV100 보다 확실한 이점이 있었다. 척수와 심장은 각각 균일 IM에서 선량증가는 있었지만 큰 차이는 없었다. Novalis ExacTrac 시스템을 이용하여 호흡연동방사선치료 시 20% 위상의 ITV설정은 균일 IM 2 mm, 40%는 3 mm를 적용함에 있어서 종양선량의 기하학적 누락 없이 최적의 치료계획을 할 수 있음을 확인하였다.

Pulmonary tuberculosis is an important public health problem. Early diagnosis and treatment is necessary for successful patient outcomes. However, diagnosis of pulmonary tuberculosis is difficult in cases with an unusual presentation and often requires a lung biopsy. The tuberculosis polymerase chain reaction results in tissue sample have potential for early diagnosis and treatment initiation for pulmonary tuberculosis. The relatively low sensitivity limit the use of this test in the detection of the pulmonary tuberculosis.

The purpose of this study was to predict occurrence of earthquakes in Korea by measuring the concentration of radon radioactivity in the air and in the underground water. Two monitoring systems of radon concentration detection in the air were installed in Seoul, East Coast area, whereas of radon concentration in the underground water in Kyungju area during December, 1999 to June, 2001. The distribution of radon concentration in the air in Seoul is as follows : winter(10.10±2.81Bq/m3), autumn(8.41±1.35Bq/m3), summer(5.83±0.05Bq/m3) and spring(5.34±0.44Bq/m3), whereas the distribution of radon in the air in the East Coast area showed some difference as follows : autumn(14.08±5.75Bq/m3), summer(12.04±0.53Bq/m3), winter(12.02±1.40Bq/m3) and spring(8.93±0.91Bq/m3). In the meanwhile, the distribution of radon in the water is as follows : spring(123.59±16.36count/10min),winter(93.95±79.69counter/10min),autumn(68.96±37.53counter/10min) and spring(34.45±9.69counter/10min). The daily range of the density of radon concentration in Seoul and East Coast area was between 5.51Bq/m3-9.44Bq/m3, 7.15Bq/m3-15.27Bq/m3, respectively. Correlation of the distributions of radon concentrations in the air and in underground water with earthquake showed considerable variations of radon concentration before the occurrence of the earthquake. The results suggested that radon radioactivity seemed to be helpful for the prediction of the occurrence of earthquake.