Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease by John Cunningham virus (JC virus) infection in oligodendrocytes. The radiographic and clinical features, along with the identification JC in cerebrospinal fluid polymerase chain reaction, are sufficient for the diagnosis of PML in immunodeficiency. However, it is difficult to suspect PML without the patient history of immunodeficiency. A 32-year-old man presented with headache for a month without any medical history. Based on clinical and image features, the differential diagnoses included demyelinating lesion and neoplasms. Microscopically, biopsy specimen showed multifocal demyelinating and degenerative white matter, consistent with PML. Oligodendrocytes cells with increased nuclei and plum-colored inclusions were admixed with perivascular lymphocytic and histiocytic infiltration, and loss of myelin. Atypical astrocytes had large or multiple nuclei. After brain biopsy, human immunodeficiency virus infection was confirmed by serum chemiluminescent immunoassay. It is unlikely that PML would be considered without the information of immunosuppression. Therefore, it is very important to be aware of the histological features of PML.

This study was carried out to investigate insect community structure from different habitats in Baengnyeong island.We performed day and night collection at two different habitats (mountain, rural area) of Baengnyeong island from Mayto September in 2015. A total of 2,879 individuals of 404 species, 81 families belonging to 10 orders were collectedand identified. A dominant species was Idisia ornata Pascoe (Tenebrionidae) despite a very low percentage (6.04%) ofthe species among the catches. Results of independent t-test showed a significant high (p<0.001) of species richness onmountain. Also, seasonal results of ANOVA (Analysis of variance) were significantly influential with species abundanceand species richness. The result of NMDS analysis showed that the community structure of the insects from the mountainis different with rural area.

Owing to climate change and global warming, foodborne infectious diseases are becoming inevitable problems in many countries, and this is also the case in Korea. One of the causal factor of foodborne disease outbreak in the food service business(i.e. restaurant or mass feeding facilities) is inappropriate management of infected food handlers. The need for strengthening of the indications for managing infected food handlers is emphasized continuously. However, precise legal interpretations or analyzation should be done based on microbiological fundamentals before strengthening the guidelines. Therefore, this study analyzes the legal policies of Korea associated with infection control of food handlers and proposes shortcomings or supplementations to existing legal policies.

Insect pollinators of the endanger orchid Cypripedium japonicum were surveyed and identified during two years, as a part of a conservation project of the orchid at Jukyeup-san and Hwaak-san (Mt.), South Korea. In total 40 individuals of 16 species in 4 families were identified. The dominant family was Halictidae, and Lasioglossum exiliceps Vachal visited the most frequently C. japonicum during the surveys. The average visiting frequency was 2.5 individuals per hour and the highest 4.3, from 12:00 – 13:00 in a day. After 15:00 insects did not visit the flowers at all. However, all of the visiting insects were found to not carry a pollinium or pollens of the orchard on their bodies; pollen carryover by any of the visiting insects did not occur at all. The orchid seems to require certain pollinators in particular body thickness due to its unique pollination mechanism. The orchid has two exit route openings, around 1 cm in diametre, where the entrapped insects can exit and an anther is situated just in front of each opening. It was inferred that a pollen carrier should be around 1 cm in body thickness. Therefore, the candidate species as the proper pollen carriers can be Tetralonia nipponensis Perez, Xylocopa appendiculata circumvolans Smith and Bombus consobrinus Dahlbom among the surveyed visitors.

The purpose of this study is to identify the bridge exercise posture for the efficient exercise by comparing the muscle activity of the lower limbs according to the changes in muscle length because of knee angle in bridge exercise. The subjects of this study were 9 randomly selected males in their 20s living in D city from those who satisfied inclusion criteria. The measured muscles were Vastus medialis oblique, Vastus lateralis, Semitendinosus, Biceps femoris, Gluteus maximus, Gluteus medius, Tensor faciae latae, and Adductor longus. Data were analyzed through paired comparison test. In the result, ST, BF, and TFL muscle activities were high when knee joint flexion angle was 90°Although in most cases higher muscle activity was shown at 90°than 60°there was no statistical significance. Interestingly, it was lower at 90°than 60°in VL. In ST, BF, and TFL, it was significantly higher at 90°han 60°(p<.05). Conclusively, knee angles in bridge exercise may affect the muscle activity, and in particular when the activity of two joint muscles such as semimenbranosus muscle, biceps femoris muscle, and tensor fasciae latae muscle increase as the angle gets higher. Therefore, it is considered that this study will provide helpful tips to develop muscular strength enforcement program for the patients with damages in the lower limbs through bridge exercise in clinical situations.

Acteoside acts as an anti-oxidative activity and anti-apoptosis in the cells. But, it has been not studied on maturation and development of porcine oocytes. The aims of the present study were to examine the effects of acteoside on the morphological progress of meiosis, developmental competence, and ROS in porcine oocytes. Oocytes were matured in tissue culture medium-199, supplemented with acteoside at various concentrations: 0 (control), 10, 30 and 50 μM. The oocytes maturation rates of groups supplemented with acteoside were no significantly different (81.13, 85.96, 82.95 and 83.68%, respectively). Level of ROS was significantly decreased in acteoside treated group. Furthermore, the parthenogenetic blastocyst rate was significantly improved in 10 μM acteoside treated group compared with control group (44.83 vs. 27.75%). And we investigated effect of acteoside on the oocytes condition represented by cytoplasmic maturation by homogeneous distribution and formation of cytoplasmic organelles and regulation of apoptosis-related genes. In the results. during IVM, 10 μM acteoside treated oocytes showed that the mitochondria and lipid droplet were smaller and homogeneous distribution in cytoplasm compare with control oocytes. And reverse transcription polymerase chain reaction (RTPCR) of parthenogenetic blstocysts revealed that acteoside increased the anti-apoptotic genes (Mcl-1, Bcl-2 and Bcl-xL), whereas reduced the expression of pro-apoptotic genes (Bax and Bak). In conclusion, based on the results, the effect of acteoside on IVM was not attractive. However, in acteoside treated group, cytoplasmic maturation seemed to be improved with morphologically uniform distribution of cytoplasmic organelles. Furthermore, embryonic development in acteoside treated group was significantly highly increased than that of non-treated group. Our results represents that addition of acteoside to the IVM medium has a beneficial effect in physiology of porcine oocytes, providing a improved method for porcine oocytes in vitro. * This work was supported by a grant (Code# PJ008148) from BioGreen21 Program, Rural Development Administration, Republic of Korea.

The absolute measurements of fluxes in the region λ λ 3 , 100 − 8 , 090 |AA emitted in the visible continua of some galactic Wolf-Rayet stars are presented. These observations were made by a two-channel scanner which was built up cooperatively by the Observatoire of Lyon and the Laboratoire d'Astronomie Spatiale. The fluxes, dereddened from those data, were combined with IUE and ANS ultraviolet measurements. These fluxes were compared with those of LTE plane paralleled model atmospheres of Kurucz (1979) and were also integrated in order to derive effective temperatures and bolometric corrections for the program stars. The derived effective temperatures and bolometric corrections for the stars were in the range of 25, 000 K ∼ 32,700 K, and of − 2.5 mag . ∼ − 3.7 mag ., respectively.