Existing reinforced concrete frame buildings designed for only gravity loads have been seismically vulnerable due to their inadequate column detailing. The seismic vulnerabilities can be mitigated by the application of a column retrofit technique, which combines high-strength near surface mounted bars with a fiber reinforced polymer wrapping system. This study presents the full-scale shaker testing of a non-ductile frame structure retrofitted using the combined retrofit system. The full-scale dynamic testing was performed to measure realistic dynamic responses and to investigate the effectiveness of the retrofit system through the comparison of the measured responses between as-built and retrofitted test frames. Experimental results demonstrated that the retrofit system reduced the dynamic responses without any significant damage on the columns because it improved flexural, shear and lap-splice resisting capacities. In addition, the retrofit system contributed to changing a damage mechanism from a soft-story mechanism (column-sidesway mechanism) to a mixed-damage mechanism, which was commonly found in reinforced concrete buildings with strong-column weak-beam system.