Velvet antler is widely used as a traditional medicine, and numerous studies have demonstrated its tremendous nutritional and medicinal values including immunity-enhancing effects. This study aimed to investigate different deer velvet extracts (Sample 1: raw extract, Sample 2: dried extract, and Sample 3: freeze-dried extract) for proximate composition, uronic acid, sulfated glycosaminoglycan, sialic acid, collagen levels, and chemical components using ultra-performance liquid chromatography-quadrupole-time-of-light mass spectrometry. In addition, we evaluated the cytotoxic effect of the deer velvet extracts on BV2 microglia, HT22 hippocampal cells, HaCaT keratinocytes, and RAW264.7 macrophages using the cell viability MTT assay. Furthermore, we evaluated acute toxicity of the deer velvet extracts at different doses (0, 500, 1000, and 2000 mg/kg) administered orally to both male and female ICR mice for 14 d (five mice per group). After treatment, we evaluated general toxicity, survival rate, body weight changes, mortality, clinical signs, and necropsy findings in the experimental mice based on OECD guidelines. The results suggested that in vitro treatment with the evaluated extracts had no cytotoxic effect in HaCaT keratinocytes cells, whereas Sample-2 had a cytotoxic effect at 500 and 1000 μg/mL on HT22 hippocampal cells and RAW264.7 macrophages. Sample 3 was also cytotoxic at concentrations of 500 and 1000 μg/mL to RAW264.7 and BV2 microglial cells. However, the mice treated in vivo with the velvet extracts at doses of 500–2000 mg/kg BW showed no clinical signs, mortality, or necropsy findings, indicating that the LD50 is higher than this dosage. These findings indicate that there were no toxicological abnormalities connected with the deer velvet extract treatment in mice. However, further human and animal studies are needed before sufficient safety information is available to justify its use in humans.

The government has recently introduced the human rights management system of public institutions in accordance with the OECD guidelines for multinational corporations and the UN guidelines for business and human rights implementation. For this reason, public institutions receive a human rights impact assessment to be reflected in the institutional management evaluation based on the human rights management manual of public institutions issued by the National Human Rights Commission of Korea. Human rights impact assessment is an institution’s management activities that identify and evaluate actual and potential human rights risks in advance and is divided into institutional and business operations. The institutional operation evaluation is conducted in 10 areas, including human rights management system, employment, labor rights, industrial safety, supply chain, and local residents’ protection, and the project operation evaluation is conducted by itself or by a specialized institution by selecting main projects and fields that can affect human rights of stakeholders. This study compares and analyzes the results of the human rights impact assessment of public institutions and specialized institutions and derives how much they contribute to improving human rights risk and respect for human rights, and what will be improved in the future. Therefore, the results of this study are expected to be of great help in the introduction and internalization of the human rights management system of public institutions.

In Korea, 483,102 assemblies of spent fuel have been discharged and stored in sites, as of 2019. However, total capacity for site storage is 529,748 assemblies, and more than 90% is already saturated. Wolsong site, the most saturated site, started to construct more dry storage to extend the capacity in 2020. Spent fuel and high-level waste (HLW) is a big concern in Korean nuclear industry. Then, master plan for management of spent fuel is once announced by Ministry of Trade, Industry and Energy (MOTIE) in 2016 and reviewed by civil committee in 2019. The core contents of the plan are establishing schedule for construction of HLW management facility in one area, and construction of temporary dry storage in each site, if unavoidable. For HLW management facility, there are three following schedules: siting of Underground Research Laboratory (URL) and Interim Storage by 2020, operation of facilities initiated by 2030, and operation of final disposal facility initiated by 2050. Final repository will be designed as deep geological repository. The concept of deep geological disposal is that spent nuclear fuel is placed in disposal containers that can withstand corrosion and pressure in long-term, permanently isolated from the human sphere of life, and dumped in deep geological media, such as crystalline rocks and clay layer, at a depth of 300 to 1,000 meters underground. The safety assessment of waste disposal sites focuses on determining whether the disposal sites meet the safety requirements of national regulatory authority. This safety assessment evaluates the potential radiation dose of radionuclides from the disposal site to humans or the environment. In this case, the calculation is performed assuming that all engineering barriers of the disposal site have collapsed in a long-term period. Then radionuclides are released from the waste, and migrated in groundwater. The dose resulting from the release and migration of radionuclides on the concentration of nuclides in groundwater. In general, metallic nuclides may exist in water in various ionic states, but some form colloids. This colloid allows more nuclides to exist in water than in solubility. Therefore, more doses may occur than we know generally predict. To determine the impact of colloids, we performed the safety assessment of the Yucca Mountain repository as an example.

Probiotic strain is known to regulate the immune system by colonizing in the intestine and interact with intestinal cell receptors of lymphoid tissue. In this study, safety of Streptococcus thermophilus KCTC14471BP and silk fibroin coating effects was evaluated with respect to mucin binding abilities and immune system modulation. S. thermophilus KCTC14471BP was coated with silk fibroin by adding 1% water-soluble calcium and 0.1% silk fibroin. S. thermophilus KCTC14471BP showed the high activities of leucine arylamidase and β-galactosidase. Regarding the antibiotic resistance tests, S. thermophilus KCTC14471BP was susceptible to ampicillin, vancomycin, gentamicin, kanamycin, streptomycin, erythromycin, clindamycin, tetracycline, and chloramphenicol. S. thermophilus KCTC14471BP coated with silk fibroin showed the improved mucin binding ability from 16.1% to 71.3% and was confirmed to have no cytotoxicity against RAW 264.7 macrophage. S. thermophilus KCTC14471BP coated with silk fibroin showed dose-dependently significant increases in pro-inflammatory cytokines IL-1β, IL-6, and TNF-α. These results suggested that S. thermophilus KCTC14471BP can be expected as a promising probiotic bacteria for applications to food industries such as fermentation or functional foods.

In this study, 38 residents of the Jeonnam areas in Korea were assessed for their level of exposure to VOCs. The aim was to understand the difference in levels of indoor, outdoor, and personal exposure to VOCs (benzene, toluene, ethylbenzene) and a health effect assessment was conducted to determine whether there was any fatal cause from carcinogenic or non-carcinogenic elements from case and control group. Personal exposure to benzene showed a higher distribution than indoor and outdoor concentrations, and it was found that the average concentration of the case group was higher than that of the control group in all indoor, outdoor, and personal exposures. With regard to benzene, in the CTE, RME, and Monte-Carlo analysis, all subjects in the case group were seen to exceed the lifetime cancer risk of 10−6 defined by the US EPA and in the RME analysis the control group subjects were also seen to exceed the lifetime cancer risk of 10−6 defined by the US EPA. In the case of toluene, ethylbenzene on the CTE, RME, and Monte-Carlo analysis, the non-carcinogenic standard of 1 was not exceeded.

본 연구는 온실의 온도와 CO2농도를 높이기 위해 DME버너용 연료로 DME가스를 사용했을 때 DME 연소가스의 성능을 결정하고 겨울에 상추와 양배추의 엽록소 함량 그리고 무게와 건조무게에 대한 영향정도를 조사하기 위해 수행되었다. 각각 온실1과 온실2에 처방 된 DME-1과 DME-2 처방은 덕트의 평균 DME 유량 17.4 m3 min-1과10.2 m3 min-1으로 구성됐으며, 대조군(DME-3)으로 남겨진 온실3에는 DME 가스가 공급되지 않 았다. DME 공급 시간은 각각 주차 별로 1주차는 하루당 0.5시간, 2주차는 1시간, 3주차는 1.5시간, 4주차는 2 시간으로 설정하였다. 각각 처방마다 엽록소 함량과 상추와 배추의 건조 전, 후 중량을 측정했으며, 연구결과 무처리구인 온실3과 비교하여 온실1과 온실2 의 CO2 농도는 각각 265%, 174% 증가하였고, 온도의 경우 4.8oC, 3.10oC 상승하였다. DME 가스를 제외한 다른 조건이 같은 온실에서 재배된 상추와 양배추의 엽록소 함량과 생체중, 건물중은 온실1에서 (유의적으로) 가장 높았으며, 온실2는 대조구 온실보다 높았다. 이러한 결과는 DME가스 연소에 의한 CO2 농도 차이에 기인된 것으로 판단된다. 일반적으로 가스연소에 의해 발생되는 유해가스 증상은 나타나지 않았으며 동절기 난방과 CO2 공급이 동시에 필요할 경우 DME가스가 기존의 경유 또는 LPG 등을 대체할 수 있는 가능성을 확인하였다. 향후 정밀한 연구를 통하여 효율적인 난방방식으로의 검토가 적극 필요하다고 판단된다.

2017년 고리 1 호기 영구정지를 계기로 국내 원자력발전소의 해체가 점차 가시화되고 있다. 앞으로 원전 해체가 본격적으로 추진될 경우 원전 1기 당 약 16만 t의 콘크리트 폐기물이 발생될 것으로 예측되었으며, 이들 콘크리트 폐기물은 대부분 오염 준위가 매우 낮아 자체처분 대상으로 고려될 수 있다. 따라서, 국내 자체처분 폐기물(원자력안전위원회 고시 2017-65호에 따른 자체처분 허용농도 또는 자체처분 허용선량을 만족하는 폐기물)에 대한 현행 규제체계가 대량의 콘크리트 폐기물에 대한 무제한적 자체처분에 대해서도 유효성을 유지할 수 있는지를 사전에 확인할 필요가 있다. 이와 관련, 국내 자체처분 규정 개발 시 참조기준인 IAEA SRS No. 44를 심층분석하고, 국내 산업계 현황을 반영한 입력값과 계산식을 이용하여 4가지 자체 처분 시나리오에 대한 예상 피폭방사선량을 평가하였다. 그 결과, 재활용 시나리오에 대한 예상선량은 대부분 정상 시나리오에 대한 자체처분 선량 기준(즉, 0.01 mSv·y-1)보다 낮은 것으로 평가되었으나, 성토 후 거주 시나리오의 경우 보수적인 가정을 적용하면 자체처분 선량 기준을 초과할 가능성도 배제할 수 없는 것으로 나타났다. 따라서, 대량의 해체 콘크리트 폐기물의 안전하고 지속가능한 자체처분을 위해서는 폐기물 처리업체 다변화, 성토 시나리오에 대한 보다 구체적인 평가, 성토를 통한 자체처분에 대한 부분적 제한조건 설정 등을 고려할 수 있다.

Purpose: The purpose of this study was to examine the effects of simulation-based training applying situation-background-assessment-recommendation on self- efficacy and communication skills in new nurses. Method: This study applied a one group pretest-posttest design, with 88 new nurses in a general hospital in S city, Korea. Data were collected from March to November 2017. The participants completed their simulation education program in 4 weeks. Data were analyzed using paired t-test with SPSS program. Results: After SBAR simulation education, self- efficacy (t=-2.40, p=.014) and communication skills (t=-5.24, p<.001) significantly improved. Conclusion: This suggests that simulation-based training applying SBAR, improved self- efficacy and communication skills in new nurses.

목 적：MRI의 RF에 의한 맥박 산소측정기 센서의 열발생으로 인해 환자에게 화상이 발생한 사례가 다수 보고되 었다. 따라서 이번 연구의 목적은 실제 임상에서 사용 되는 MRI 시퀀스에서의 열 발생을 정량적으로 측정하고자 하였다. 대상 및 방법：3.0 T MRI(Ingenia, Philips, Netherlands)장치와 광섬유 온도계(FTX-301-PWR 3ch Temperature transmitter, OSENSA, Canada), 하이드록시에틸 셀룰로즈와 염화나트륨을 혼합한 겔 용액을 넣은 팬텀을 사용하였다. 위치 변화에 따른 실험은 맥박 산소측정기를 중앙부와 좌측 외측부에 설치한 후 세 부위의 isocenter에서 SAR 3.2 W/kg으로 15분간 스캔하며 온도를 측정하였다. 임상 조건 에서의 온도측정 실험은 맥박 산소측정기를 환자의 왼손 위치인 팬텀 좌하측 측면에 고정하고, Brain, C-spine, L-spine의 임상조건으로 스캔하며 온도를 측정하였다 결 과：맥박 산소측정기의 위치에 따른 실험 중 정중앙 위치에서는 isocenter 1, 2, 3에서 각각 1.6, 2.7, 1.2 ℃의 온도상승을 나타냈고, 좌측 외측부 위치에서는 각각 10.8, 9.9, 9.9 ℃의 온도상승을 나타냈다. 임상조건에서는 Brain, C-spine, L-spine 스캔에서 각각 10.3, 6.3, 3.9 ℃의 온도상승이 나타났다. 결 론：본 연구를 통해 MRI의 RF로 인한 맥박 산소측정기의 발열현상과 이로 인한 접촉 부위의 화상발생 가능 성을 직접적인 온도측정 실험을 통해 확인할 수 있었다.

목 적：MRI의 RF에 의한 맥박 산소측정기 센서의 열발생으로 인해 환자에게 화상이 발생한 사례가 다수 보고되었다. 따라서 이번 연구의 목적은 실제 임상에서 사용 되는 MRI 시퀀스에서의 열 발생을 정량적으로 측정하고자 하였다. 대상 및 방법：3.0 T MRI(Ingenia, Philips, Netherlands)장치와 광섬유 온도계(FTX-301-PWR 3ch Temperature transmitter, OSENSA, Canada), 하이드록시에틸 셀룰로즈와 염화나트륨을 혼합한 겔용액을 넣은 팬텀을 사용하였다. 위치 변화에 따른 실험은 맥박 산소측정기를 중앙부와 좌측 외측부에 설치한 후 세 부위의 isocenter에서 SAR 3.2 W/kg으로 15분간 스캔하며 온도를 측정하였다. 임상 조건에서의 온도측정 실험은 맥박 산소측정기를 환자의 왼손 위치인 팬텀 좌하측 측면에 고정하고, Brain, C-spine, L-spine의 임상조건으로 스캔하며 온도를 측정하였다 결 과：맥박 산소측정기의 위치에 따른 실험 중 정중앙 위치에서는 isocenter 1, 2, 3에서 각각 1.6, 2.7, 1.2 ℃의 온도상승을 나타냈고, 좌측 외측부 위치에서는 각각 10.8, 9.9, 9.9 ℃의 온도상승을 나타냈다. 임상조건에서는 Brain, C-spine, L-spine 스캔에서 각각 10.3, 6.3, 3.9 ℃의 온도상승이 나타났다. 결 론：본 연구를 통해 MRI의 RF로 인한 맥박 산소측정기의 발열현상과 이로 인한 접촉 부위의 화상발생 가능성을 직접적인 온도측정 실험을 통해 확인할 수 있었다.

The purpose of our study was to determine the effect of Maitland orthopedic manual therapy, Silver Spike Point, dietary fiber and gymnastic exercise on the improvement of constipation. Forty patients with constipation participated in the study (Maitland Orthopedic Manual Therapy Group(n=10), Silver Spike Point Therapy Group(n=10), Dietary Fiber Group(n=10) and Gymnastics Exercise Group(n=10)). The assessment scale and weekly bowel frequency were measured before and after the experiment. Assessment scale was significantly increased in Silver Spike Point Therapy, Maitland orthopedic therapy, gymnastic exercise compare to dietary fiber. Weekly bowel frequency was significantly increased in gymnastic exercise compared to dietary fiber. The results of this study suggest that Silver Spike Point Therapy, Maitland orthopedic therapy, gymnastic exercise improve the symptom in patients with constipation.

본 연구는 영상의 시간적 요소를 제어하였을 때 어떠한 감성적 효과가 나타나는가를 탐구하였고, 연구 결과를 기반으 로 영상 감성 평가 도구를 개발하였다. 연구는 두 단계로 나누어 진행되었다. 첫 번째 연구에서는 원본 영상 대비 영상의 재생 스타일 적용이 야기할 수 있는 감성적 가치를 수집하고자 하였다. 영상의 배속, 방향성, 연속성 등 세 가지 시간적 요소를 제어해 총 11 가지의 재생 스타일을 설정하였다. 그리고 재생 스타일 각각에 대하여 원본 영상과 견주어 어떠한 감성적 효과가 부가되는가를 어휘 형태로 수집하였다. 원본 영상으로는 중성적인 감성과 네 개의 감성 영상 ― 기쁨, 여유로움, 화남, 슬픔 ― 을 활용하였다. 실험을 통해 (N=30) 총 3,800 개의 단어들이 수집되었으며, 위 단어들은 899 종의 감성 어휘로 정리되었다. 그리고 감성 어휘들은 유의어 관계에 의해 총 52 가지의 감성 어휘 군집으로 최종 분류되었다. 두 번째 연구에서는 재생 스타일이 적용된 영상의 감성을 평가하는 도구를 개발하고자 하였다. 연구의 자극물로 재생 스타일이 적용된 11 가지 상업적 영상물을 수집하고, 각 영상을 재생 스타일이 적용되지 않은 원본 영상으로 변환하였다. 그리고 첫 번째 실험과 같이 재생 스타일이 적용된 영상과 원본 영상을 동시에 제시해, 재생 스타일에 의한 효과를 평가하였다. 평가자들은 (N=30) 감성 어휘 899 종 가운데 선별된 대표적인 영상 감성 어휘 38개에 대해 5 점 척도로 응답하였다. 요인 분석법을 통해 응답을 분석한 결과 총 4개의 감성 요인 ― 기쁨, 슬픔, 회상적, 이상함 ― 이 추출되었다. 이 4개 요인은 보편적인 정서 이론가 비교하여 기쁨과 슬픔이 공존한다는 차이점을 나타내었다. 추가적으로, 연구 결과를 토대로 애니메이션 기반의 감성 평가 도구를 개발한 후 이에 대한 활용 가치 및 응용 방안에 대하여 논의하였다.

Information on spatial distribution and peak occurrence is important for site and time specific pest management. So, we investigated seasonal occurrence and edge distribution of major soybean pests by visual count in six commercial fields located in Andong from July 16 to October 23 in 2015. We found a total of 19 species in 10 families. The major pest during vegetative stage was Medythia nigrobilineata (Motschulsky) while Riptortus pedestris (Fabricius) and Halyomorpha halys (Stal) showed peak occurrence during reproductive stage of soybean. Aphis glycines Matsumura was found throughout the season. Seasonal density of M. nigrobilineata was 0.20 and 0.38/plant in edge and interior without significance, respectively. The infestation of A. glycine was also found similar between edge and interior. Immatures of R. pedestris and H. halys distributed more in edge (0.21 and 0.36/plant) than interior (0.12 and 0.12/plant), respectively. The application of these informations on spatial distribution pattern of soybean pest was discussed.

Deposits discharged through the cleaning mainly were cement mortar, bitumen paintings and rust pieces, and fragments of perforation, stones and gravels. Deposits were more removed through swabbing pig cleaning rather than air scouring cleaning on the whole. However, air scouring cleaning were not influenced by the constraint conditions such as a change in the diameter or the presence of the valve in water mains compare to swabbing pig cleaning. So, it was thought that air scouring cleaning might be more favorable to water distribution network cleaning in the future. After the cleaning, water quality including residual chlorine and turbidity also was improved because of the removal of a significant amount of the deposits. Therefore, if the cleaning is continuously and regularly implemented in water mains, it is expected that it will help to recover the reliability and to preserve the health of water quality.

본 연구는 라벤더 향과 레몬 향을 포함하는 방향성 의류소재에 힐링효과가 있는지 알아보고자 신체 반응인 자 율신경계 반응을 평가하였다. 이를 위해 라벤더와 레몬향의 마이크로캡슐과 수성 아크릴 바인더를 사용하여 면직 물에 코팅처리 하여 각각 2%, 5%의 농도로 처리 된 라벤더와 레몬향의 방향성 의류소재 총 4종을 만들었다. 심전도, 피부전도수준, 혈류량의 실험 참여자는 10명 이었으며, 안정 상태에서 30초, 스트레스 상태 (working memory task) 30초, 향 자극 상태(방향성 섬유를 비벼 향을 나게 한 후) 30초를 측정하였다. 그리고 주관적 감성 평가도 함 께 실시하였다. 데이터를 분석하기 위해 표준화를 해주었으며, 표준화 값에 대하여 안정 상태와 자극 상태의 생리 신호 차이와, 스트레스 상태와 자극 상태의 생리신호 차이를 알아보기 위해 비모수검정 Friedman 검증을 통해 그 경향을 분석 하였다. 자율신경 발란스 지수(LF/HF)는 스트레스 유발 후 향 자극 상태와 유의한 차이가 있어 사후 검증 하였다. 그 결과 레몬 5%의 향 자극은 라벤더 2%, 라벤더 5%, 레몬 2%의 향 자극과 유의한 차이가 있었다. 스트레스 유발 후 레몬 5%의 향 자극은 스트레스를 증가 시켰으나 라벤더 2%, 라벤더 5%, 레몬 2%의 향 자극은 심리적 안정을 유발하여 스트레스를 감소시켰으며 본 논문에서 힐링효과를 나타냈다.

This study was to inspect how the portfolio assessment in physical education classes affects the learning attitude and the improvement of motor skills. The experimental group of 40 students utilized the portfolio assessment and the control group of 40 students were tested with a traditional assessment. A test paper on learning attitude and a measure on assessment of motor skills was estimated of reliability and validity. After a vaulting horse-rolling instructions were practiced 11 sessions for 4 weeks that the experimental group were tested with portfolio assessment. The control group were tested with traditional assessment. Each group took a posttest about learning attitude and motor skills. The collected data through the posttest were analyzed with t-test. The findings of this study could be listed as follows; First, the learning attitude of experimental group using the portfolio assessment was better than the control group, and the difference was significant statistically. Second, the motor skills of experimental group using the portfolio assessment were better than the control group, and the difference was significant statistically.

Various anti-scattering agents for suppression of dust scattering at waste depository were compared in this study. Based on the price, easy of usage, and no toxicity, 1% of Al2(SO4)3 was selected as surface hardening agents. Only lower than 2% of total weight were flied when wind speed was monthly maximum velocity during 1 hr. These results were quite good with comparison of S anti-scattering agents which was made by C company in Korea. When Al2(SO4)3 was spread, the surface waste became hard therefore the effect of suppression of scattering dust was long lasting. It was recommend that 2% of Al2(SO4)3 was spread to keep suppression of scattering dust when sudden gust of wind such as natural disaster was occurred.

ln this paper, we proposed the modified method of Metcalfe ’s law that is “ Modfied law" in evalllating the network power for the measurement of combat effectiveness in C41 system. It is applied to JFOS-K (Joint Fire Operating SystemKorea) C41 system that